[HTML][HTML] Selection bias on intellectual ability in autism research: A cross-sectional review and meta-analysis
Background Current global estimates suggest the proportion of the population with autism
spectrum disorder (ASD) who have intellectual disability (ID) is approximately 50%. Our�…
spectrum disorder (ASD) who have intellectual disability (ID) is approximately 50%. Our�…
[HTML][HTML] State of the field: Differentiating intellectual disability from autism spectrum disorder
The topic of this special issue on secondary versus idiopathic autism allows for discussion of
how different groups may come to manifest autism spectrum disorder (ASD) or ASD-like�…
how different groups may come to manifest autism spectrum disorder (ASD) or ASD-like�…
Patterns of de novo tandem repeat mutations and their role in autism
Autism spectrum disorder (ASD) is an early-onset developmental disorder characterized by
deficits in communication and social interaction and restrictive or repetitive behaviours�…
deficits in communication and social interaction and restrictive or repetitive behaviours�…
Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and�…
Y Wang, N Li, JJ Yang, DM Zhao, B Chen…�- Pharmacological�…, 2020 - Elsevier
The prevalence of autism spectrum disorders (ASD) is increasing, but its etiology remains
elusive and hence an effective treatment is not available. Previous research conducted on�…
elusive and hence an effective treatment is not available. Previous research conducted on�…
Molecular diagnostic yield of chromosomal microarray analysis and whole-exome sequencing in children with autism spectrum disorder
Importance The use of genome-wide tests to provide molecular diagnosis for individuals
with autism spectrum disorder (ASD) requires more study. Objective To perform�…
with autism spectrum disorder (ASD) requires more study. Objective To perform�…
Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons
INTRODUCTION SHANK3 is a scaffolding protein that is enriched in postsynaptic densities
of excitatory synapses but ubiquitously expressed in most cells. SHANK3 gene mutations�…
of excitatory synapses but ubiquitously expressed in most cells. SHANK3 gene mutations�…
Advances in the genetics and neuropathology of tuberous sclerosis complex: edging closer to targeted therapy
P Curatolo, N Specchio, E Aronica�- The Lancet Neurology, 2022 - thelancet.com
Tuberous sclerosis complex is a rare genetic disease associated with mutations in the TSC1
or TSC2 genes, which cause overactivation of the mTOR complex. In the past 5 years�…
or TSC2 genes, which cause overactivation of the mTOR complex. In the past 5 years�…
[HTML][HTML] Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex
Gene expression levels vary across developmental stage, cell type, and region in the brain.
Genomic variants also contribute to the variation in expression, and some neuropsychiatric�…
Genomic variants also contribute to the variation in expression, and some neuropsychiatric�…
Autism spectrum disorder and epilepsy: two sides of the same coin?
SS Jeste, R Tuchman�- Journal of child neurology, 2015 - journals.sagepub.com
Autism spectrum disorders and epilepsy commonly co-occur. In this review, we consider
some unresolved questions regarding the temporal relationship, causal mechanisms, and�…
some unresolved questions regarding the temporal relationship, causal mechanisms, and�…
[HTML][HTML] ASD validity
L Waterhouse, E London, C Gillberg�- Review Journal of Autism and�…, 2016 - Springer
ASD research is at an important crossroads. The ASD diagnosis is important for assigning a
child to early behavioral intervention and explaining a child's condition. But ASD research�…
child to early behavioral intervention and explaining a child's condition. But ASD research�…