Although KDM5C is one of the most frequently mutated genes in X-linked intellectual
disability, the exact mechanisms that lead to cognitive impairment remain unknown. Here we�…

The 17p13. 3 chromosome region is often deleted or duplicated in humans, resulting in
severe neurodevelopmental disorders such as Miller–Dieker syndrome (MDS) and 17p13. 3�…

The brainstem includes many nuclei and fiber tracts that mediate a wide range of functions.
Data from two parallel approaches to the study of autistic spectrum disorder (ASD) implicate�…

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the
leading single-gene form of autism spectrum disorder, encompassing cognitive, behavioral�…

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. FXS is
an X-linked, neurodevelopmental disorder caused by a CGG trinucleotide repeat expansion�…

Perinatal air pollution plays an important role in the development of autism. However,
research on the pathogenic mechanism remains limited. In this study, the model of systemic�…

The application of ambient mass spectrometry imaging “MSI” is expanding in the areas of
fundamental research on drug delivery and multiple phases of the process of identifying and�…

Loss of fragile X retardation protein (FMRP) leads to fragile X syndrome (FXS), a common
cause of inherited intellectual disability. Protein lysine acetylation (K-ac), a reversible post�…

Introduction Autism spectrum disorder (ASD) is a persistent neurodevelopmental condition
characterized by two core behavioral symptoms: impaired social communication and�…

Multiple lines of evidence suggest that a deficiency of Fragile X Mental Retardation Protein
(FMRP) mediates dysfunction of the metabotropic glutamate receptor subtype 5 (mGluR5) in�…