Predictive models are essential for advancing knowledge of brain disorders. High variation
in study outcomes hampers progress. To address the validity of predictive models, we�…

The role of oxytocin (OT) as a neuropeptide that modulates social behavior has been
extensively studied and reviewed, but beyond these functions, OT's adaptive functions at�…

Short tandem repeat (STR) instability causes transcriptional silencing in several repeat
expansion disorders. In fragile X syndrome (FXS), mutation-length expansion of a CGG STR�…

Autism spectrum disorder (ASD) has a multifactorial etiology. Major efforts are underway to
understand the neurobiological bases of ASD and to develop efficacious treatment�…

Fragile X syndrome (FXS) is caused by silencing of the human FMR1 gene and is the
leading monogenic cause of intellectual disability and autism. Abundant preclinical data�…

Autism spectrum disorder (ASD) is a neurodevelopmental condition primarily characterized
by an impairment of social interaction combined with the occurrence of repetitive behaviors�…

Unrelated genetic mutations can lead to convergent manifestations of neurological disorders
with similar behavioral phenotypes. Experimental data frequently show a lack of dramatic�…

Neurodevelopmental disorders (NDDs) that affect cognition, social interaction, and learning,
including autism spectrum disorder (ASD) and intellectual disability (ID), have a strong�…

Autism spectrum disorders (ASDs) are characterized by repetitive behaviors and
impairments of sociability and communication. About 1% of ASD cases are caused by�…

Analysis of the chemical makeup of the brain enables a deeper understanding of several
neurological processes. Molecular imaging that deciphers the spatial distribution of�…