The prevalence and cost of chronic pain is a major physical and mental health care problem
in the United States today. As a result, there has been a recent explosion of research on�…

CONTEXT: The perception of pain due to an acute injury or in clinical pain states undergoes
substantial processing at supraspinal levels. Supraspinal, brain mechanisms are�…

What neural mechanism underlies the capacity to understand the emotions of others? Does
this mechanism involve brain areas normally involved in experiencing the same emotion�…

Neuroeconomics is the study of the neurobiological and computational basis of value-based
decision making. Its goal is to provide a biologically based account of human behaviour that�…

Placebo effects are beneficial effects that are attributable to the brain–mind responses to the
context in which a treatment is delivered rather than to the specific actions of the drug. They�…

Brain responses to pain, assessed through positron emission tomography (PET) and
functional magnetic resonance imaging (fMRI) are reviewed. Functional activation of brain�…

The experience of pain arises from both physiological and psychological factors, including
one's beliefs and expectations. Thus, placebo treatments that have no intrinsic�…

The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery�…

Recently, there has been a convergence in lesion and neuroimaging data in the
identification of circuits underlying positive and negative emotion in the human brain�…

Numerous languages characterize 'social pain', the feelings resulting from social
estrangement, with words typically reserved for describing physical pain ('broken�…