[HTML][HTML] An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity
E Masini, E Loi, AF Vega-Benedetti, M Carta…�- International journal of�…, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly�…
interaction and communication, with restricted interests, activity and behaviors. ASD is highly�…
Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based�…
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based�…
[HTML][HTML] Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Cortical circuits are composed predominantly of pyramidal-to-pyramidal neuron
connections, yet their assembly during embryonic development is not well understood. We�…
connections, yet their assembly during embryonic development is not well understood. We�…
Data-driven diagnostics and the potential of mobile artificial intelligence for digital therapeutic phenotyping in computational psychiatry
P Washington, N Park, P Srivastava, C Voss…�- Biological Psychiatry�…, 2020 - Elsevier
Data science and digital technologies have the potential to transform diagnostic
classification. Digital technologies enable the collection of big data, and advances in�…
classification. Digital technologies enable the collection of big data, and advances in�…
[HTML][HTML] Emerging mechanisms of valproic acid-induced neurotoxic events in autism and its implications for pharmacological treatment
A Taleb, W Lin, X Xu, G Zhang, QG Zhou…�- Biomedicine &�…, 2021 - Elsevier
Autism spectrum disorder (ASD) is a sort of mental disorder marked by deficits in cognitive
and communication abilities. To date no effective cure for this pernicious disease has been�…
and communication abilities. To date no effective cure for this pernicious disease has been�…
[HTML][HTML] Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers-pre-clinical and clinical investigations
J Prata, SG Santos, MI Almeida, R Coelho…�- Journal of�…, 2017 - Springer
In recent years, evidence supporting a link between inflammation and neuropsychiatric
disorders has been mounting. Autism spectrum disorders (ASD) and schizophrenia share�…
disorders has been mounting. Autism spectrum disorders (ASD) and schizophrenia share�…
[HTML][HTML] A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1�…
The genetic etiology and underlying mechanism of autism spectrum disorder (ASD) remain
elusive. SHANK family genes (SHANK1/2/3) are well known ASD-related genes. However�…
elusive. SHANK family genes (SHANK1/2/3) are well known ASD-related genes. However�…
Rare variants and the oligogenic architecture of autism
T Wang, PA Zhao, EE Eichler�- Trends in Genetics, 2022 - cell.com
Most large-scale genetic studies of autism have focused on the discovery of genes by
proving an enrichment of de novo mutations (DNMs) in autism probands or characterizing�…
proving an enrichment of de novo mutations (DNMs) in autism probands or characterizing�…
[HTML][HTML] EEG features in autism Spectrum disorder: a retrospective analysis in a cohort of preschool children
ME Santarone, S Zambrano, N Zanotta, E Mani…�- Brain Sciences, 2023 - mdpi.com
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that can be
associated with intellectual disability (ID) and epilepsy (E). The etiology and the�…
associated with intellectual disability (ID) and epilepsy (E). The etiology and the�…
Recent advances in understanding inheritance of holoprosencephaly
C Dubourg, A Kim, E Watrin…�- American Journal of�…, 2018 - Wiley Online Library
Holoprosencephaly (HPE) is a complex genetic disorder of the developing forebrain
characterized by high phenotypic and genetic heterogeneity. HPE was initially defined as an�…
characterized by high phenotypic and genetic heterogeneity. HPE was initially defined as an�…