Background & Aims Multiple environmental factors have been associated with the
development of inflammatory bowel diseases (IBDs). We performed an umbrella review of�…

Females and males differ in the energy consumption and nutritional requirements which are
based on the interactions between environmental factors and sex hormones (1). The studies�…

Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting�…

The X chromosome and X-linked variants have largely been ignored in genome-wide and
candidate association studies of infectious diseases due to the complexity of statistical�…

Objective: To examine whether childhood traumatic stress increased the risk of developing
autoimmune diseases as an adult. Methods: Retrospective cohort study of 15,357 adult�…

Abstract Purpose of Review As the ongoing epidemic of adult and childhood obesity grows,
it puts a greater burden on individuals and the healthcare system due to increased�…

People aged 60 and older represent over 11% of the world population and it is expected to
rise 22% by 2050. Population aging is associated to an increased frequency of age-related�…

Objective To determine the incidence and disease‐specific predictors of clinically
recognized psoriatic arthritis (PsA) in patients with psoriasis. Methods We identified an�…

Autoimmune diseases are characterized by a significant sex dimorphism, with women
showing increased susceptibility to disease. This is, at least in part, due to sex-dependent�…

Over the last decades, a central role for vitamin D in immune modulation has been well
established. The active form of vitamin D, ie, 1, 25-dihydroxyvitamin D, through the�…