Single nucleotide variations encoding missense mutations in G protein‐coupled receptors may contribute to autism

ET van der Westhuizen�- British Journal of Pharmacology, 2023 - Wiley Online Library
Autism is a neurodevelopmental condition with a range of symptoms that vary in intensity
and severity from person to person. Genetic sequencing has identified thousands of genes�…

[HTML][HTML] Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum�…

DI Mohamed, HH Abo Nahas, AM Elshaer…�- Frontiers in Cellular�…, 2023 - frontiersin.org
Autism spectrum disorders (ASD) represent a diverse group of neuropsychiatric conditions,
and recent evidence has suggested a connection between ASD and microbial dysbiosis�…

Deficiency of FRMD5 results in neurodevelopmental dysfunction and autistic-like behavior in mice

TJ Lyu, J Ma, XY Zhang, GG Xie, C Liu, J Du…�- Molecular�…, 2024 - nature.com
The pathophysiology of autism spectrum disorders (ASDs) is causally linked to postsynaptic
scaffolding proteins, as evidenced by numerous large-scale genomic studies [,] and in vitro�…

Cancer and neurodevelopmental disorders: multi-scale reasoning and computational guide

R Nussinov, BR Yavuz, HC Demirel, MK Arici…�- Frontiers in Cell and�…, 2024 - frontiersin.org
The connection and causality between cancer and neurodevelopmental disorders have
been puzzling. How can the same cellular pathways, proteins, and mutations lead to�…

Emerging functions and therapeutic targets of IL‐38 in central nervous system diseases

Y Gao, L Cai, Y Wu, M Jiang, Y Zhang…�- CNS Neuroscience�…, 2024 - Wiley Online Library
Abstract Interleukin (IL)‐38 is a newly discovered cytokine of the IL‐1 family, which binds
various receptors (ie, IL‐36R, IL‐1 receptor accessory protein‐like 1, and IL‐1R1) in the�…

[HTML][HTML] SCGN deficiency is a risk factor for autism spectrum disorder

Z Liu, S Tan, L Zhou, L Chen, M Liu, W Wang…�- …�and Targeted Therapy, 2023 - nature.com
Autism spectrum disorder (ASD) affects 1–2% of all children and poses a great social and
economic challenge for the globe. As a highly heterogeneous neurodevelopmental disorder�…

Exposure to Bisphenol F and Bisphenol S during development induces autism-like endophenotypes in adult Drosophila melanogaster

EAS Musachio, S da Silva Andrade, LB Meichtry…�- Neurotoxicology and�…, 2024 - Elsevier
Abstract Bisphenol F (BPF) and Bisphenol S (BPS) are being widely used by the industry
with the claim of “safer substances”, even with the scarcity of toxicological studies. Given the�…

[HTML][HTML] Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability

J Wen, I Skampardoni, YE Tian, Z Yang, Y Cui, G Erus…�- medRxiv, 2023 - ncbi.nlm.nih.gov
Disease heterogeneity poses a significant challenge for precision diagnostics in both clinical
and sub-clinical stages. Recent work leveraging artificial intelligence (AI) has offered�…

Between Dysbiosis, Maternal Immune Activation and Autism: Is There a Common Pathway?

M Suprunowicz, N Tomaszek, A Urbaniak…�- Nutrients, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a neuropsychiatric condition characterized by impaired
social interactions and repetitive stereotyped behaviors. Growing evidence highlights an�…

High-fat diet-induced obesity causes intestinal Th17/Treg imbalance that impairs the intestinal barrier and aggravates anxiety-like behavior in mice

Y Cai, W Deng, Q Yang, G Pan, Z Liang, X Yang…�- International�…, 2024 - Elsevier
The prevalence of autism spectrum disorders (ASD) has been steadily increasing, and
growing evidence suggests a link between high-fat diet (HFD), obesity, and ASD; however�…