[HTML][HTML] Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy

L Wang, B Wang, C Wu, J Wang, M Sun�- International journal of�…, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism�…

[HTML][HTML] mTOR signaling disruption and its association with the development of autism spectrum disorder

SD Thomas, NK Jha, S Ojha, B Sadek�- Molecules, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic�…

[HTML][HTML] Inflammatory mediators drive neuroinflammation in autism spectrum disorder and cerebral palsy

UTT Than, LT Nguyen, PH Nguyen, XH Nguyen…�- Scientific Reports, 2023 - nature.com
Inflammation conditions are associated with autism spectrum disorder (ASD) and cerebral
palsy (CP), primarily observed in the peripheral immune system. However, the extent of�…

[HTML][HTML] Autistic spectrum disorder (ASD)–Gene, molecular and pathway signatures linking systemic inflammation, mitochondrial dysfunction, transsynaptic signalling�…

M Gevezova, Y Sbirkov, V Sarafian, K Plaimas…�- Brain, behavior, &�…, 2023 - Elsevier
Background Despite advances in autism spectrum disorder (ASD) research and the vast
genomic, transcriptomic, and proteomic data available, there are still controversies�…

[HTML][HTML] Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview

N Lampiasi, R Bonaventura, I Deidda, F Zito…�- International Journal of�…, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of�…

[HTML][HTML] Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: A systematic review and meta-analysis

M Ding, S Shi, S Qie, J Li, X Xi�- Frontiers in pediatrics, 2023 - frontiersin.org
Background Studies have found that toxic heavy metals exposure could induce the
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might be�…

[HTML][HTML] Dendritic spine and synapse pathology in chromatin modifier-associated autism spectrum disorders and intellectual disability

TJL Ford, BT Jeon, H Lee, WY Kim�- Frontiers in molecular�…, 2023 - frontiersin.org
Formation of dendritic spine and synapse is an essential final step of brain wiring to
establish functional communication in the developing brain. Recent findings have displayed�…

[HTML][HTML] Role of gastrointestinal health in managing children with autism spectrum disorder

M Al-Beltagi, NK Saeed, AS Bediwy…�- World journal of�…, 2023 - ncbi.nlm.nih.gov
Children with autism spectrum disorders (ASD) or autism are more prone to gastrointestinal
(GI) disorders than the general population. These disorders can significantly affect their�…

[HTML][HTML] Recent developments in autism genetic research: A scientometric review from 2018 to 2022

M Lim, A Carollo, D Dimitriou, G Esposito�- Genes, 2022 - mdpi.com
Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence�…

[HTML][HTML] Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome

BR Yavuz, MK Arici, HC Demirel, CJ Tsai…�- NPJ genomic�…, 2023 - nature.com
Epidemiological studies suggest that individuals with neurodevelopmental disorders (NDDs)
are more prone to develop certain types of cancer. Notably, however, the case statistics can�…