[HTML][HTML] Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses

A Modabbernia, E Velthorst, A Reichenberg�- Molecular autism, 2017 - Springer
Background According to recent evidence, up to 40–50% of variance in autism spectrum
disorder (ASD) liability might be determined by environmental factors. In the present paper�…

[HTML][HTML] Composition of gut microbiota in children with autism spectrum disorder: a systematic review and meta-analysis

L Iglesias-V�zquez, G Van Ginkel Riba, V Arija…�- Nutrients, 2020 - mdpi.com
Background: Autism spectrum disorder (ASD) is a public health problem and has a
prevalence of 0.6%–1.7% in children. As well as psychiatric symptoms, dysbiosis and�…

Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity

R Hanamsagar, MD Alter, CS Block, H Sullivan…�- Glia, 2017 - Wiley Online Library
Evidence suggests many neurological disorders emerge when normal neurodevelopmental
trajectories are disrupted, ie, when circuits or cells do not reach their fully mature state�…

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister�- Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and�…

Environmental risk factors and biomarkers for autism spectrum disorder: an umbrella review of the evidence

JY Kim, MJ Son, CY Son, J Radua, M Eisenhut…�- The Lancet�…, 2019 - thelancet.com
Background Numerous studies have identified potential risk factors and biomarkers for
autism spectrum disorder. We aimed to study the strength and validity of the suggested�…

Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis

A Masi, DS Quintana, N Glozier, AR Lloyd…�- Molecular�…, 2015 - nature.com
The role of non-diagnostic features in the pathophysiology of autism spectrum disorders
(ASDs) is unclear. Increasing evidence suggests immune system alterations in ASD may be�…

[HTML][HTML] Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders

S Dash, YA Syed, MR Khan�- Frontiers in Cell and Developmental�…, 2022 - frontiersin.org
The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome�…

[HTML][HTML] High intelligence: A risk factor for psychological and physiological overexcitabilities

RI Karpinski, AMK Kolb, NA Tetreault, TB Borowski�- Intelligence, 2018 - Elsevier
High intelligence is touted as being predictive of positive outcomes including educational
success and income level. However, little is known about the difficulties experienced among�…

[HTML][HTML] The immune system, cytokines, and biomarkers in autism spectrum disorder

A Masi, N Glozier, R Dale, AJ Guastella�- Neuroscience bulletin, 2017 - Springer
Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental condition
characterized by variable impairments in communication and social interaction as well as�…

[HTML][HTML] Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism

DA Rossignol, RE Frye�- Frontiers in physiology, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD�…