Maternal immune activation: Implications for neuropsychiatric disorders

ML Estes, AK McAllister�- Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that�…

[HTML][HTML] The contribution of environmental exposure to the etiology of autism spectrum disorder

S B�lte, S Girdler, PB Marschik�- Cellular and Molecular Life Sciences, 2019 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their�…

[HTML][HTML] The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water�- Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused�…

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister�- Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and�…

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions�…

Autoimmunity, autoantibodies, and autism spectrum disorder

E Edmiston, P Ashwood, J Van de Water�- Biological psychiatry, 2017 - Elsevier
Auism spectrum disorder (ASD) now affects one in 68 births in the United States and is the
fastest growing neurodevelopmental disability worldwide. Alarmingly, for the majority of�…

[HTML][HTML] Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz�- Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of�…

[HTML][HTML] The impact of neuroimmune alterations in autism spectrum disorder

C Gottfried, V Bambini-Junior, F Francis…�- Frontiers in�…, 2015 - frontiersin.org
Autism spectrum disorder (ASD) involves a complex interplay of both genetic and
environmental risk factors, with immune alterations and synaptic connection deficiency in�…

[HTML][HTML] Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism

A Ramirez-Celis, M Becker, M Nu�o, J Schauer…�- Molecular�…, 2021 - nature.com
The incidence of autism spectrum disorder (ASD) has been rising, however ASD-risk
biomarkers remain lacking. We previously identified the presence of maternal�…

[HTML][HTML] Repetitive restricted behaviors in autism spectrum disorder: From mechanism to development of therapeutics

J Tian, X Gao, L Yang�- Frontiers in neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors�…