In vitro functional profiling of fentanyl and nitazene analogs at the μ-opioid receptor reveals high efficacy for Gi protein signaling

MHM Tsai, L Chen, MH Baumann…�- ACS Chemical�…, 2024 - ACS Publications
Novel synthetic opioids (NSOs), including both fentanyl and non-fentanyl analogs that act as
μ-opioid receptor (MOR) agonists, are associated with serious intoxication and fatal�…

Preclinical evidence for the use of the atypical antipsychotic, brexpiprazole, for opioid use disorder

JER Nickols, SM Dursun, AMW Taylor�- Neuropharmacology, 2023 - Elsevier
Opioid addiction is characterized by adaptations in the mesolimbic dopamine system that
occur during chronic opioid use. Alterations in dopaminergic transmission contribute to�…

A scoping review of mHealth technologies for opioid overdose prevention, detection and response

B Tas, W Lawn, EV Traykova, RAS Evans…�- Drug and Alcohol�…, 2023 - Wiley Online Library
Issues Opioid overdose kills over 100,000 people each year globally. Mobile health
(mHealth) technologies and devices, including wearables, with the capacity to prevent�…

The gender-diversity and autism questionnaire: A community-developed clinical, research, and self-advocacy tool for autistic transgender and gender-diverse young�…

JF Strang, LS McClellan, D Raaijmakers…�- Autism in�…, 2023 - liebertpub.com
Background: Autistic transgender people face unique risks in society, including inequities in
accessing needed care and related mental health disparities. Given the need for specific�…

[HTML][HTML] Opioid agonist treatment take-home doses ('carries'): Are current guidelines resulting in low treatment coverage among high-risk populations in Canada and�…

C Russell, S Lange, F Kouyoumdjian, A Butler…�- Harm Reduction�…, 2022 - Springer
Opioid agonist treatment (OAT) is the primary intervention for opioid use disorder (OUD) in
Canada and the USA. Yet, a number of barriers contribute to sub-optimal treatment uptake�…

Is alexithymia related to retention and relapses in patients with substance use disorders?: A one year follow-up study

RF Palma-�lvarez, E Ros-Cucurull, C Daigre…�- Addictive�…, 2021 - Elsevier
Alexithymia is related to a higher severity of substance use disorders (SUD); however, few
longitudinal studies have been performed on how alexithymia impacts treatment outcomes�…

How autistic adults' priorities for autism research differ by gender identity: A mixed-methods study

OC Putnam, G Eddy, J Goldblum, M Swisher…�- Women's�…, 2023 - journals.sagepub.com
Background: Recent studies suggest that the funding breakdown of autism research in the
United States may not align with stakeholder priorities. Furthermore, the majority of�…

Gender and Autism Program: A novel clinical service model for gender-diverse/transgender autistic youth and young adults

JF Strang, AL Fischbach, S Rao…�- The Clinical�…, 2024 - Taylor & Francis
Abstract Objective: Situated in Children's National Hospital (CNH)'s Neuropsychology
Division, the Gender and Autism Program (GAP) is the first clinical service dedicated to the�…

Medication treatment for alcohol use disorder in special populations

A Malhotra, K Drexler, M Hsu…�- The American Journal on�…, 2023 - Wiley Online Library
Abstract Background and Objectives Alcohol use disorder (AUD) is a significant public
health concern, with underutilized effective treatments, particularly in special populations�…

[HTML][HTML] Prolonged-release buprenorphine formulations: perspectives for clinical practice

M Chappuy, B Trojak, P Nubukpo, J Bachellier…�- Therapies, 2020 - Elsevier
Buprenorphine and methadone are the two main opioid agonist treatments approved for
opioid use disorder. Buprenorphine is a partial agonist of the mu opioid receptors, which has�…