In vitro functional profiling of fentanyl and nitazene analogs at the μ-opioid receptor reveals high efficacy for Gi protein signaling
MHM Tsai, L Chen, MH Baumann…�- ACS Chemical�…, 2024 - ACS Publications
Novel synthetic opioids (NSOs), including both fentanyl and non-fentanyl analogs that act as
μ-opioid receptor (MOR) agonists, are associated with serious intoxication and fatal�…
μ-opioid receptor (MOR) agonists, are associated with serious intoxication and fatal�…
Preclinical evidence for the use of the atypical antipsychotic, brexpiprazole, for opioid use disorder
Opioid addiction is characterized by adaptations in the mesolimbic dopamine system that
occur during chronic opioid use. Alterations in dopaminergic transmission contribute to�…
occur during chronic opioid use. Alterations in dopaminergic transmission contribute to�…
A scoping review of mHealth technologies for opioid overdose prevention, detection and response
Issues Opioid overdose kills over 100,000 people each year globally. Mobile health
(mHealth) technologies and devices, including wearables, with the capacity to prevent�…
(mHealth) technologies and devices, including wearables, with the capacity to prevent�…
The gender-diversity and autism questionnaire: A community-developed clinical, research, and self-advocacy tool for autistic transgender and gender-diverse young�…
JF Strang, LS McClellan, D Raaijmakers…�- Autism in�…, 2023 - liebertpub.com
Background: Autistic transgender people face unique risks in society, including inequities in
accessing needed care and related mental health disparities. Given the need for specific�…
accessing needed care and related mental health disparities. Given the need for specific�…
[HTML][HTML] Opioid agonist treatment take-home doses ('carries'): Are current guidelines resulting in low treatment coverage among high-risk populations in Canada and�…
C Russell, S Lange, F Kouyoumdjian, A Butler…�- Harm Reduction�…, 2022 - Springer
Opioid agonist treatment (OAT) is the primary intervention for opioid use disorder (OUD) in
Canada and the USA. Yet, a number of barriers contribute to sub-optimal treatment uptake�…
Canada and the USA. Yet, a number of barriers contribute to sub-optimal treatment uptake�…
Is alexithymia related to retention and relapses in patients with substance use disorders?: A one year follow-up study
RF Palma-�lvarez, E Ros-Cucurull, C Daigre…�- Addictive�…, 2021 - Elsevier
Alexithymia is related to a higher severity of substance use disorders (SUD); however, few
longitudinal studies have been performed on how alexithymia impacts treatment outcomes�…
longitudinal studies have been performed on how alexithymia impacts treatment outcomes�…
How autistic adults' priorities for autism research differ by gender identity: A mixed-methods study
OC Putnam, G Eddy, J Goldblum, M Swisher…�- Women's�…, 2023 - journals.sagepub.com
Background: Recent studies suggest that the funding breakdown of autism research in the
United States may not align with stakeholder priorities. Furthermore, the majority of�…
United States may not align with stakeholder priorities. Furthermore, the majority of�…
Gender and Autism Program: A novel clinical service model for gender-diverse/transgender autistic youth and young adults
JF Strang, AL Fischbach, S Rao…�- The Clinical�…, 2024 - Taylor & Francis
Abstract Objective: Situated in Children's National Hospital (CNH)'s Neuropsychology
Division, the Gender and Autism Program (GAP) is the first clinical service dedicated to the�…
Division, the Gender and Autism Program (GAP) is the first clinical service dedicated to the�…
Medication treatment for alcohol use disorder in special populations
A Malhotra, K Drexler, M Hsu…�- The American Journal on�…, 2023 - Wiley Online Library
Abstract Background and Objectives Alcohol use disorder (AUD) is a significant public
health concern, with underutilized effective treatments, particularly in special populations�…
health concern, with underutilized effective treatments, particularly in special populations�…
[HTML][HTML] Prolonged-release buprenorphine formulations: perspectives for clinical practice
M Chappuy, B Trojak, P Nubukpo, J Bachellier…�- Therapies, 2020 - Elsevier
Buprenorphine and methadone are the two main opioid agonist treatments approved for
opioid use disorder. Buprenorphine is a partial agonist of the mu opioid receptors, which has�…
opioid use disorder. Buprenorphine is a partial agonist of the mu opioid receptors, which has�…