A 'fourth wave'of high mortality involving methamphetamine and cocaine use has been
gathering force in the USA. Availability and use of illicit fentanyls are still the major drivers of�…

Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered�…

Background: Transgender healthcare is a rapidly evolving interdisciplinary field. In the last
decade, there has been an unprecedented increase in the number and visibility of�…

Because nonopioid analgesics are much sought after, we computationally docked more
than 301 million virtual molecules against a validated pain target, the α2A-adrenergic�…

Despite an estimated heritability of~ 50%, genome-wide association studies of opioid use
disorder (OUD) have revealed few genome-wide significant loci. We conducted a cross�…

Today's LGBTQ youth come of age at a time of dynamic social and political change with
regard to LGBTQ rights and visibility, yet remain vulnerable to compromised mental health�…

Social isolation during opioid withdrawal is a major contributor to the current opioid
addiction crisis. We find that sociability deficits during protracted opioid withdrawal in mice�…

Objective Autism spectrum disorder (ASD) is significantly over-represented among
transgender adolescents. Independently, ASD and gender diversity are associated with�…

Drug, alcohol and tobacco use disorders are a global burden affecting millions of people.
Despite decades of research, treatment options are sparse or missing, and relapse rates are�…

Emerging research suggests overrepresentation of gender diversity among autistic youth.
Previous gender diversity research with autistic children has relied on parent-report based�…