Specific and effective treatments for autism spectrum disorder (ASD) are lacking due to a
poor understanding of disease mechanisms. Here we test the idea that similarities between�…

Fragile X syndrome (FXS), a disorder of synaptic development and function, is the most
prevalent genetic form of intellectual disability and autism spectrum disorder. FXS mouse�…

Epilepsy and autism spectrum disorder (ASD) are highly mutually comorbid, suggesting
potential overlaps in genetic etiology, pathophysiology, and neurodevelopmental�…

Objective The etiology of autism spectrum disorder (ASD) remains unclear, due to genetic
heterogeneity and heterogeneity in symptoms across individuals. This study compares ASD�…

Autism spectrum disorder (ASD) is a highly heritable, complex disorder in which rare
variants contribute significantly to disease risk. Although many genes have been associated�…

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the
leading single-gene form of autism spectrum disorder, encompassing cognitive, behavioral�…

Aberrant condensation and localisation of the RNA-binding protein (RBP) fused in sarcoma
(FUS) occur in variants of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia�…

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders that cause
severe social, communication, and behavioral problems. Recent studies show that the�…

In non-polarized cells, nonsense-mediated mRNA decay (NMD) generally begins during the
translation of newly synthesized mRNAs after the mRNAs are exported to the cytoplasm�…

The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is
associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its�…