The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities�…

Background Innovative technologies, such as machine learning, big data, and artificial
intelligence (AI) are approaches adopted for personalized medicine, and psychological�…

Background In this modern era, depression is one of the most prevalent mental disorders
from which millions of individuals are affected today. The symptoms of depression are�…

Background Psychological therapies are effective for treating major depressive disorder, but
current clinical guidelines do not provide guidance on the personalization of treatment�…

Major depressive disorder (MDD) is the leading cause of disability worldwide, yet treatment
selection still proceeds via “trial and error”. Given the varied presentation of MDD and�…

Ketamine is a NMDA receptor antagonist that has a rapid acting antidepressant effect with
high efficacy in treatment-resistant patients. Ketamine is a beneficial antidepressant for�…

Artificial intelligence is disrupting the field of mental healthcare through applications in
computational psychiatry, which leverages quantitative techniques to inform our�…

Depression is a kind of emotion that negatively impacts people's daily lives. The number of
people suffering from long-term feelings is increasing every year across the globe�…

Background: Approximately two-thirds of patients with major depressive disorder do not
achieve remission during their first treatment. There has been increasing interest in the use�…

Clinical decision support systems (CDSS) augmented with artificial intelligence (AI) models
are emerging as potentially valuable tools in healthcare. Despite their promise, the�…