Model of autism: increased ratio of excitation/inhibition in key neural systems
JLR Rubenstein, MM Merzenich�- Genes, Brain and Behavior, 2003 - Wiley Online Library
Autism is a severe neurobehavioral syndrome, arising largely as an inherited disorder,
which can arise from several diseases. Despite recent advances in identifying some genes�…
which can arise from several diseases. Despite recent advances in identifying some genes�…
The amygdala theory of autism
Brothers (Brothers L. Concepts in Neuroscience 1990; 1: 27–51) proposed a network of
neural regions that comprise the “social brain”, which includes the amygdala. Since the�…
neural regions that comprise the “social brain”, which includes the amygdala. Since the�…
Neuroglial activation and neuroinflammation in the brain of patients with autism
DL Vargas, C Nascimbene, C Krishnan…�- Annals of Neurology�…, 2005 - Wiley Online Library
Autism is a neurodevelopmental disorder characterized by impaired communication and
social interaction and may be accompanied by mental retardation and epilepsy. Its cause�…
social interaction and may be accompanied by mental retardation and epilepsy. Its cause�…
Impairment of social and moral behavior related to early damage in human prefrontal cortek
SW Anderson, A Bechara, H Damasio…�- Social�…, 2013 - taylorfrancis.com
The long-term consequences of early prefrontal cortex lesions occurring before 16 months
were investigated in two adults. As is the case when such damage occurs in adulthood, the�…
were investigated in two adults. As is the case when such damage occurs in adulthood, the�…
Social intelligence in the normal and autistic brain: an fMRI study
S Baron‐Cohen, HA Ring…�- European journal of�…, 1999 - Wiley Online Library
There is increasing support for the existence of 'social intelligence'[Humphrey (1984)
Consciousness Regained], independent of general intelligence. Brothers et al.(1990) J�…
Consciousness Regained], independent of general intelligence. Brothers et al.(1990) J�…
Brain structural abnormalities in young children with autism spectrum disorder
BF Sparks, SD Friedman, DW Shaw, EH Aylward…�- Neurology, 2002 - AAN Enterprises
Objective: To explore the specific gross neuroanatomic substrates of this brain
developmental disorder, the authors examine brain morphometric features in a large sample�…
developmental disorder, the authors examine brain morphometric features in a large sample�…
Epilepsy in autism
R Tuchman, I Rapin�- The Lancet Neurology, 2002 - thelancet.com
There is an increased but variable risk of epilepsy in autism. Three main factors—age,
cognitive level, and type of language disorder—account for variability in the reported�…
cognitive level, and type of language disorder—account for variability in the reported�…
Sleep behaviors and sleep quality in children with autism spectrum disorders
MC Souders, TBA Mason, O Valladares, M Bucan…�- Sleep, 2009 - academic.oup.com
Abstract Study Objectives:(1) Compare sleep behaviors of children with autism spectrum
disorders (ASD) with sleep behaviors of typically developing (TD) children using the�…
disorders (ASD) with sleep behaviors of typically developing (TD) children using the�…
Postmortem brain abnormalities of the glutamate neurotransmitter system in autism
AE Purcell, OH Jeon, AW Zimmerman, ME Blue…�- Neurology, 2001 - AAN Enterprises
Background: Studies examining the brains of individuals with autism have identified
anatomic and pathologic changes in regions such as the cerebellum and hippocampus�…
anatomic and pathologic changes in regions such as the cerebellum and hippocampus�…
Immunity, neuroglia and neuroinflammation in autism
CA Pardo, DL Vargas…�- International review of�…, 2005 - Taylor & Francis
Autism is a complex neurodevelopmental disorder of early onset that is highly variable in its
clinical presentation. Although the causes of autism in most patients remain unknown�…
clinical presentation. Although the causes of autism in most patients remain unknown�…