[HTML][HTML] Epilepsy and attention deficit hyperactivity disorder: connection, chance, and challenges
Comorbidities are common in children with epilepsy, with nearly half of the patients having
at least one comorbidity. Attention deficit hyperactivity disorder (ADHD) is a psychiatric�…
at least one comorbidity. Attention deficit hyperactivity disorder (ADHD) is a psychiatric�…
[HTML][HTML] Single cell spatial biology over developmental time can decipher pediatric brain pathologies
R Nussinov, BR Yavuz, H Jang�- Neurobiology of Disease, 2024 - Elsevier
Pediatric low grade brain tumors and neurodevelopmental disorders share proteins,
signaling pathways, and networks. They also share germline mutations and an impaired�…
signaling pathways, and networks. They also share germline mutations and an impaired�…
[HTML][HTML] Epilepsy: a multifaced spectrum disorder
Epilepsy is one of the most widespread chronic conditions, affecting about 50 million people
worldwide. It consists of a group of neurological disorders characterized by recurrent�…
worldwide. It consists of a group of neurological disorders characterized by recurrent�…
[HTML][HTML] Epilepsy phenotype and gene ontology analysis of the 129 genes in a large neurodevelopmental disorders cohort
YJ Ko, SY Kim, S Lee, JG Yoon, MJ Kim, H Jun…�- Frontiers in�…, 2023 - frontiersin.org
Objective Although pediatric epilepsy is an independent disease entity, it is often observed
in pediatric neurodevelopmental disorders (NDDs) as a major or minor clinical feature�…
in pediatric neurodevelopmental disorders (NDDs) as a major or minor clinical feature�…
[HTML][HTML] DLG3 variants caused X-linked epilepsy with/without neurodevelopmental disorders and the genotype-phenotype correlation
YY He, S Luo, L Jin, PY Wang, J Xu, HL Jiao…�- Frontiers in Molecular�…, 2024 - frontiersin.org
Background The DLG3 gene encodes disks large membrane-associated guanylate kinase
scaffold protein 3, which plays essential roles in the clustering of N-methyl-D-aspartate�…
scaffold protein 3, which plays essential roles in the clustering of N-methyl-D-aspartate�…
[HTML][HTML] The ATP6V1B2 DDOD/DOORS-Associated p.Arg506* Variant Causes Hyperactivity and Seizures in Mice
J Rousseau, SB Tene Tadoum, M Lavertu Jolin…�- Genes, 2023 - mdpi.com
The vacuolar H+-ATPase is a multisubunit enzyme which plays an essential role in the
acidification and functions of lysosomes, endosomes, and synaptic vesicles. Many genes�…
acidification and functions of lysosomes, endosomes, and synaptic vesicles. Many genes�…
Advances in understanding the pathogenesis of epilepsy: Unraveling the molecular mechanisms
S Shariff, HA Nouh, S Inshutiyimana…�- Health Science�…, 2024 - Wiley Online Library
Introduction Epilepsy is characterized by having two or more unprovoked seizures.
Understanding the pathogenesis of epilepsy, requires deep investigation into the molecular�…
Understanding the pathogenesis of epilepsy, requires deep investigation into the molecular�…
Psychiatric comorbidities in epilepsy: population co-occurrence, genetic correlations and causal effects
Background: Psychiatric comorbidities are common in patients with epilepsy. Reasons for
the co-occurrence of psychiatric conditions and epilepsy remain poorly understood. Aim: We�…
the co-occurrence of psychiatric conditions and epilepsy remain poorly understood. Aim: We�…
Onset of Inattention and Hyperactivity in Children and Adolescents With Epilepsy 6 months After the Diagnosis
Ž Rogač, D Stevanović, S Bečanović…�- Journal of Attention�…, 2023 - journals.sagepub.com
Objective: Complete or major symptoms of ADHD are often present in epilepsy. This study
evaluated inattention and hyperactivity symptoms over the first 6 months in newly diagnosed�…
evaluated inattention and hyperactivity symptoms over the first 6 months in newly diagnosed�…
Dendritic arbor dynamics and stability in health and disease
M Mlostek, J Zeng, M Urbanska, J Jaworski�- Acta Neurobiologiae�…, 2023 - ane.pl
Dendritogenesis, a process of dendritic arbor development, is essential for the formation of
functional neuronal networks, and in mammals, it begins in early life and continues into�…
functional neuronal networks, and in mammals, it begins in early life and continues into�…