[HTML][HTML] Neuroinflammation in Parkinson's disease and its potential as therapeutic target

Q Wang, Y Liu, J Zhou�- Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and�…

Emerging roles for the gut microbiome in autism spectrum disorder

HE Vuong, EY Hsiao�- Biological psychiatry, 2017 - Elsevier
Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one
in 45 children in the United States, with a similarly striking prevalence in countries around�…

[HTML][HTML] The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water�- Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused�…

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions�…

Elevated maternal C-reactive protein and autism in a national birth cohort

AS Brown, A Sourander, S Hinkka-Yli-Salom�ki…�- Molecular�…, 2014 - nature.com
Autism is a complex neuropsychiatric syndrome with a largely unknown etiology.
Inflammation during pregnancy may represent a common pathway by which infections and�…

[HTML][HTML] Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders

TC Theoharides, I Tsilioni, AB Patel, R Doyle�- Translational psychiatry, 2016 - nature.com
Autism spectrum disorders (ASDs) affect as many as 1 in 45 children and are characterized
by deficits in sociability and communication, as well as stereotypic movements. Many�…

[HTML][HTML] Autism spectrum disorders and neuropathology of the cerebellum

DR Hampson, GJ Blatt�- Frontiers in neuroscience, 2015 - frontiersin.org
The cerebellum contains the largest number of neurons and synapses of any structure in the
central nervous system. The concept that the cerebellum is solely involved in fine motor�…

Recent advances in our understanding of mast cell activation–or should it be mast cell mediator disorders?

TC Theoharides, I Tsilioni, H Ren�- Expert review of clinical�…, 2019 - Taylor & Francis
Introduction: An increasing number of patients present with multiple symptoms affecting
many organs including the brain due to multiple mediators released by mast cells. These�…

Biomarkers in autism spectrum disorder: the old and the new

B Ruggeri, U Sarkans, G Schumann, AM Persico�- Psychopharmacology, 2014 - Springer
Rationale Autism spectrum disorder (ASD) is a complex heterogeneous
neurodevelopmental disorder with onset during early childhood and typically a life-long�…

[HTML][HTML] Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz�- Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of�…