Involvement of extrasynaptic glutamate in physiological and pathophysiological changes of neuronal excitability

B P�l�- Cellular and Molecular Life Sciences, 2018 - Springer
Glutamate is the most abundant neurotransmitter of the central nervous system, as the
majority of neurons use glutamate as neurotransmitter. It is also well known that this�…

[HTML][HTML] Astrocytes, noradrenaline, α1-adrenoreceptors, and neuromodulation: evidence and unanswered questions

J Wahis, MG Holt�- Frontiers in cellular neuroscience, 2021 - frontiersin.org
Noradrenaline is a major neuromodulator in the central nervous system (CNS). It is released
from varicosities on neuronal efferents, which originate principally from the main�…

[HTML][HTML] The dynamic nature of percolation on networks with triadic interactions

H Sun, F Radicchi, J Kurths, G Bianconi�- Nature Communications, 2023 - nature.com
Percolation establishes the connectivity of complex networks and is one of the most
fundamental critical phenomena for the study of complex systems. On simple networks�…

Information propagation in multilayer systems with higher-order interactions across timescales

G Nicoletti, DM Busiello�- Physical Review X, 2024 - APS
Complex systems are characterized by multiple spatial and temporal scales. A natural
framework to capture their multiscale nature is that of multilayer networks, where different�…

[HTML][HTML] Enteric glia: a new player in abdominal pain

W Morales-Soto, BD Gulbransen�- Cellular and molecular gastroenterology�…, 2019 - Elsevier
Chronic abdominal pain is the most common gastrointestinal issue and contributes to the
pathophysiology of functional bowel disorders and inflammatory bowel disease. Current�…

[HTML][HTML] And then there was light: perspectives of optogenetics for deep brain stimulation and neuromodulation

J Delbeke, L Hoffman, K Mols, D Braeken…�- Frontiers in�…, 2017 - frontiersin.org
Deep Brain Stimulation (DBS) has evolved into a well-accepted add-on treatment for
patients with severe Parkinsons disease as well as for other chronic neurological conditions�…

Astrocyte‐derived adenosine excites sleep‐promoting neurons in the ventrolateral preoptic nucleus: Astrocyte‐neuron interactions in the regulation of sleep

IS Choi, JH Kim, JY Jeong, MG Lee, K Suk, IS Jang�- Glia, 2022 - Wiley Online Library
Although ATP and/or adenosine derived from astrocytes are known to regulate sleep, the
precise mechanisms underlying the somnogenic effects of ATP and adenosine remain�…

[HTML][HTML] Chemogenetic activation of astrocytes in the basolateral amygdala contributes to fear memory formation by modulating the amygdala–prefrontal cortex�…

Z Lei, L Xie, CH Li, YY Lam, AS Ramkrishnan…�- International Journal of�…, 2022 - mdpi.com
The basolateral amygdala (BLA) is one of the key brain areas involved in aversive learning,
especially fear memory formation. Studies of aversive learning in the BLA have largely�…

Neuroimmune impacts of early-life stress on development and psychopathology

HC Brenhouse, A Danese, R Grassi-Oliveira�- …�regulation of behavior, 2019 - Springer
Maltreatment and trauma in childhood, termed early-life stress (ELS), has long-term effects
on the immune system. ELS impacts immune signaling at the time of exposure but also�…

Stimulation of water and calcium dynamics in astrocytes with pulsed infrared light

AI Borrachero‐Conejo, WR Adams…�- The FASEB�…, 2020 - Wiley Online Library
Astrocytes are non‐neuronal cells that govern the homeostatic regulation of the brain
through ions and water transport, and Ca2+‐mediated signaling. As they are tightly�…