Dilated cardiomyopathy: genetic determinants and mechanisms

EM McNally, L Mestroni�- Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing�…

Evolving concepts in dilated cardiomyopathy

M Merlo, A Cannata, M Gobbo, D Stolfo…�- European journal of�…, 2018 - Wiley Online Library
Dilated cardiomyopathy (DCM) represents a particular aetiology of systolic heart failure that
frequently has a genetic background and usually affects young patients with few co�…

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy

JA Towbin, WJ McKenna, DJ Abrams, MJ Ackerman…�- Heart rhythm, 2019 - Elsevier
Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a�…

Recommendations for participation in competitive and leisure time sport in athletes with cardiomyopathies, myocarditis, and pericarditis: position statement of the Sport�…

A Pelliccia, EE Solberg, M Papadakis…�- European Heart�…, 2019 - academic.oup.com
Myocardial diseases are associated with an increased risk of potentially fatal cardiac
arrhythmias and sudden cardiac death/cardiac arrest during exercise, including hypertrophic�…

Genetic risk of arrhythmic phenotypes in patients with dilated cardiomyopathy

M Gigli, M Merlo, SL Graw, G Barbati…�- Journal of the American�…, 2019 - jacc.org
Background: Genotype-phenotype correlations in dilated cardiomyopathy (DCM) and, in
particular, the effects of gene variants on clinical outcomes remain poorly understood�…

Dilated cardiomyopathy and arrhythmogenic left ventricular cardiomyopathy: a comprehensive genotype-imaging phenotype study

JB Augusto, R Eiros, E Nakou…�- European Heart�…, 2020 - academic.oup.com
Aims Myocardial scar detected by cardiovascular magnetic resonance has been associated
with sudden cardiac death in dilated cardiomyopathy (DCM). Certain genetic causes of DCM�…

Phenotypic expression, natural history, and risk stratification of cardiomyopathy caused by filamin C truncating variants

M Gigli, D Stolfo, SL Graw, M Merlo, C Gregorio…�- Circulation, 2021 - Am Heart Assoc
Background: Filamin C truncating variants (FLNCtv) cause a form of arrhythmogenic
cardiomyopathy: the mode of presentation, natural history, and risk stratification of FLNCtv�…

[HTML][HTML] Mitochondrial function and dysfunction in dilated cardiomyopathy

D Ramaccini, V Montoya-Uribe, FJ Aan…�- Frontiers in cell and�…, 2021 - frontiersin.org
Cardiac tissue requires a persistent production of energy in order to exert its pumping
function. Therefore, the maintenance of this function relies on mitochondria that represent�…

[PDF][PDF] 2018 ESC Guidelines for the diagnosis and management of syncope

M Brignole, A Moya, FJ De Lange…�- Polish Heart�…, 2018 - journals.viamedica.pl
Pierwsze wytyczne ESC dotyczące postępowania w omdleniach opublikowano w 2001
roku, a ich kolejne wersje w latach 2004 i 2009. W marcu 2015 roku CPG uznała, że�…

Arrhythmias as presentation of genetic cardiomyopathy

J Lukas Laws, MC Lancaster…�- Circulation�…, 2022 - Am Heart Assoc
There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias�…