[HTML][HTML] Early estimates of nirsevimab immunoprophylaxis effectiveness against hospital admission for respiratory syncytial virus lower respiratory tract infections in�…

M L�pez-Lacort, C Mu�oz-Quiles…�- …, 2024 - eurosurveillance.org
The monoclonal antibody nirsevimab was at least 70% effective in preventing
hospitalisations in infants with lower respiratory tract infections (LRTI) positive for respiratory�…

[HTML][HTML] Impact of nirsevimab prophylaxis on paediatric respiratory syncytial virus (RSV)-related hospitalisations during the initial 2023/24 season in Luxembourg

C Ernst, D Bejko, L Gaasch, E Hannelas…�- …, 2024 - eurosurveillance.org
After Luxembourg introduced nirsevimab immunisation against respiratory syncytial virus
(RSV), estimated neonatal coverage was 84%(1,277 doses/1,524 births) in 2023. That year�…

Effectiveness and impact of universal prophylaxis with nirsevimab in infants against hospitalisation for respiratory syncytial virus in Galicia, Spain: initial results of a�…

S Ares-G�mez, N Mallah, MI Santiago-P�rez…�- The Lancet Infectious�…, 2024 - thelancet.com
Summary Background Galicia (Spain) was one of the first regions worldwide to incorporate
nirsevimab for universal respiratory syncytial virus (RSV) prophylaxis in infants into its�…

Nirsevimab and Hospitalization for RSV Bronchiolitis

Z Assad, AS Romain, C Aupiais, M Shum…�- …�England Journal of�…, 2024 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis, resulting
in 3 million hospitalizations each year worldwide. Nirsevimab is a monoclonal antibody�…

New and Emerging Passive Immunization Strategies for the Prevention of RSV Infection During Infancy

JB Domachowske�- Journal of the Pediatric Infectious Diseases�…, 2024 - academic.oup.com
To date, safe and effective strategies to prevent medically attended RSV illness across the
infant population have been limited to passive immunoprophylaxis for those at highest risk�…

Impact of Nirsevimab Immunization on Pediatric Hospitalization rates: A Systematic Review and Meta-Analysis (2024)

M Ricc�, A Cascio, S Corrado, M Bottazzoli, F Marchesi…�- Vaccines, 2024 - mdpi.com
A systematic review with a meta-analysis was performed to gather available evidence on the
effectiveness of monoclonal antibody nirsevimab in the prevention of lower respiratory tract�…

[HTML][HTML] Effectiveness of nirsevimab immunoprophylaxis against respiratory syncytial virus-related outcomes in hospital and primary care settings: a retrospective�…

E Coma, M Martinez-Marcos, E Hermosilla…�- Archives of Disease in�…, 2024 - adc.bmj.com
Background In Catalonia, infants under 6 months old were eligible to receive nirsevimab, a
novel monoclonal antibody against respiratory syncytial virus (RSV). We aimed to analyse�…

Effectiveness of nirsevimab immunoprophylaxis administered at birth to prevent infant hospitalisation for respiratory syncytial virus infection: A population-based cohort�…

G Ezpeleta, A Navascu�s, N Viguria…�- Vaccines, 2024 - mdpi.com
Respiratory syncytial virus (RSV) infection is a frequent cause of hospitalisation in the first
few months of life; however, this risk rapidly decreases with age. Nirsevimab�…

[HTML][HTML] Safety and Efficacy of Nirsevimab in a Universal Prevention Program of Respiratory Syncytial Virus Bronchiolitis in Newborns and Infants in the First Year of�…

A Consolati, M Farinelli, P Serravalle, C Rollandin…�- Vaccines, 2024 - mdpi.com
Respiratory syncytial virus (RSV) bronchiolitis remains a significant global health burden,
particularly in newborns and infants during their first year of life. The quest for an effective�…

Short‐and mid‐term morbidity and primary‐care burden due to infant respiratory syncytial virus infection: A Spanish 6‐year population‐based longitudinal study

S Ares‐G�mez, N Mallah, J Pardo‐Seco…�- Pediatric Allergy and�…, 2024 - Wiley Online Library
Background The morbidity burden of respiratory syncytial virus (RSV) in infants extends
beyond hospitalization. Defining the RSV burden before implementing prophylaxis�…