Mitochondria are vital organelles with distinct morphological features and functional
properties. The dynamic network of mitochondria undergoes structural and functional�…

Ischaemic heart disease is a leading cause of death worldwide. Injury to the heart is
followed by loss of the damaged cardiomyocytes, which are replaced with fibrotic scar�…

Single cardiomyocytes contain myofibrils that harbor the sarcomere-based contractile
machinery of the myocardium. Cardiomyocytes differentiated from human pluripotent stem�…

In addition to their use in relieving the symptoms of various diseases, ketogenic diets (KDs)
have also been adopted by healthy individuals to prevent being overweight. Herein, we�…

Rationale: Both fusion and fission contribute to mitochondrial quality control. How
unopposed fusion affects survival of cardiomyocytes and left ventricular function in the heart�…

With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers�…

It is increasingly acknowledged that a sex and gender specificity affects the occurrence,
development, and consequence of a plethora of pathologies. Mitochondria are considered�…

Mitochondria have emerged as key participants in and regulators of myocardial injury during
ischemia and reperfusion. This review examines the sites of damage to cardiac�…

Mitochondrial dynamics and mitophagy have been linked to cardiovascular and
neurodegenerative diseases. Here, we demonstrate that the mitochondrial division dynamin�…

Aging can be seen as process characterized by accumulation of oxidative stress induced
damage. Oxidative stress derives from different endogenous and exogenous processes, all�…