[HTML][HTML] A synaptic perspective of fragile X syndrome and autism spectrum disorders
C Bagni, RS Zukin�- Neuron, 2019 - cell.com
Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are�…
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are�…
16p11. 2 copy number variations and neurodevelopmental disorders
Copy number variations (CNVs) of the human 16p11. 2 genetic locus are associated with a
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual�…
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual�…
[HTML][HTML] Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
Neurodevelopmental disorders have a heritable component and are associated with region
specific alterations in brain anatomy. However, it is unclear how genetic risks for�…
specific alterations in brain anatomy. However, it is unclear how genetic risks for�…
Vascular contributions to 16p11. 2 deletion autism syndrome modeled in mice
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled,
vascular contributions to ASD remain elusive. Here, we investigated postnatal�…
vascular contributions to ASD remain elusive. Here, we investigated postnatal�…
[HTML][HTML] A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases
Genes associated with risk for brain disease exhibit characteristic expression patterns that
reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of�…
reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of�…
Behavioral neuroscience of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models�…
of ASD have been identified and this has enabled researchers to construct mouse models�…
[HTML][HTML] Emerging behavioral and neuroimaging biomarkers for early and accurate characterization of autism spectrum disorders: a systematic review
The possibility of early treatment and a better outcome is the direct product of early
identification and characterization of any pathological condition. Autism spectrum disorder�…
identification and characterization of any pathological condition. Autism spectrum disorder�…
The link between autism and sex-related neuroanatomy, and associated cognition and gene expression
Objective: The male preponderance in prevalence of autism is among the most pronounced
sex ratios across neurodevelopmental conditions. The authors sought to elucidate the�…
sex ratios across neurodevelopmental conditions. The authors sought to elucidate the�…
[HTML][HTML] Optogenetic activation of striatal D1R and D2R cells differentially engages downstream connected areas beyond the basal ganglia
The basal ganglia (BG) are a group of subcortical nuclei responsible for motor and executive
function. Central to BG function are striatal cells expressing D1 (D1R) and D2 (D2R)�…
function. Central to BG function are striatal cells expressing D1 (D1R) and D2 (D2R)�…
[HTML][HTML] The functional neural architecture of dysfunctional reward processing in autism
Functional imaging studies have found differential neural activation patterns during reward-
paradigms in patients with autism spectrum disorder (ASD) compared to neurotypical�…
paradigms in patients with autism spectrum disorder (ASD) compared to neurotypical�…