Cortical morphometric vulnerability to generalised epilepsy reflects chromosome‐and cell type‐specific transcriptomic signatures
Aims Generalised epilepsy is thought to involve distributed brain networks. However, the
molecular and cellular factors that render different brain regions more vulnerable to�…
molecular and cellular factors that render different brain regions more vulnerable to�…
Compressed primary‐to‐transmodal gradient is accompanied with subcortical alterations and linked to neurotransmitters and cellular signatures in major depressive�…
Y Xiao, L Zhao, X Zang, SW Xue�- Human Brain Mapping, 2023 - Wiley Online Library
Major depressive disorder (MDD) has been shown to involve widespread changes in low‐
level sensorimotor and higher‐level cognitive functions. Recent research found that a�…
level sensorimotor and higher‐level cognitive functions. Recent research found that a�…
Molecular signatures of attention networks
Attention network theory proposes three distinct types of attention—alerting, orienting, and
control—that are supported by separate brain networks and modulated by different�…
control—that are supported by separate brain networks and modulated by different�…
Human cortex development is shaped by molecular and cellular brain systems
Human brain morphology undergoes complex developmental changes with diverse regional
trajectories. Various biological factors influence cortical thickness development, but human�…
trajectories. Various biological factors influence cortical thickness development, but human�…
[HTML][HTML] Network connectivity and local transcriptomic vulnerability underpin cortical atrophy progression in Parkinson's disease
Parkinson's disease pathology is hypothesized to spread through the brain via axonal
connections between regions and is further modulated by local vulnerabilities within those�…
connections between regions and is further modulated by local vulnerabilities within those�…
Gene expression has distinct associations with brain structure and function in major depressive disorder
Major depressive disorder (MDD) is associated with structural and functional brain
abnormalities. MDD as well as brain anatomy and function are influenced by genetic factors�…
abnormalities. MDD as well as brain anatomy and function are influenced by genetic factors�…
[HTML][HTML] Lifestyle Factors Counteract the Neurodevelopmental Impact of Genetic Risk for Accelerated Brain Aging in Adolescence
Background The transition from childhood to adolescence is characterized by enhanced
neural plasticity and a consequent susceptibility to both beneficial and adverse aspects of�…
neural plasticity and a consequent susceptibility to both beneficial and adverse aspects of�…
[HTML][HTML] Unraveling the molecular relevance of brain phenotypes: A comparative analysis of null models and test statistics
Correlating transcriptional profiles with imaging-derived phenotypes has the potential to
reveal possible molecular architectures associated with cognitive functions, brain�…
reveal possible molecular architectures associated with cognitive functions, brain�…
[HTML][HTML] Assortative mixing in micro-architecturally annotated brain connectomes
The wiring of the brain connects micro-architecturally diverse neuronal populations, but the
conventional graph model, which encodes macroscale brain connectivity as a network of�…
conventional graph model, which encodes macroscale brain connectivity as a network of�…
How Do Neurotransmitter Pathways Contribute to Neuroimaging Phenotypes?
Neuroimaging could accurately reflect human behaviour in health and disease, but the
mechanism by which image-derived phenotypes correspond to neurotransmitter systems�…
mechanism by which image-derived phenotypes correspond to neurotransmitter systems�…