Abstract Interleukin‐17 s (IL‐17s) are well‐known proinflammatory cytokines, and their
antagonists perform excellently in the treatment of inflammatory skin diseases such as�…

Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is�…

Psoriasis is an instructive example highlighting our growing knowledge about
pathophysiological functions of interleukin (IL)‐17. IL‐17A is the predominant isoform�…

Background Interleukin (IL)-23, a member of the IL-12 family, has emerged as an important
cytokine that bridges the innate and adaptive immune systems and plays a critical role in the�…

Psoriasis is a common chronic inflammatory skin disease, associated with substantial
comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived�…

Psoriasis is a frequent chronic inflammatory skin disease, nowadays considered a major
global health problem. Several new drugs, targeting the IL-23/IL-17A pathway, have been�…

Emerging data in mice and humans reveals a critical contribution of Th17-associated
cytokines, particularly interleukin-(IL)-23 and IL-17, in the pathogenesis of psoriasis. The IL�…

Plaque psoriasis is an autoinflammatory and autoimmune skin disease, affecting 1-3% of the
population worldwide. Previously, high levels of IL-36 family cytokines were found in�…

Summary Interleukin (IL)‐17 is an emerging target for inflammatory skin disorders. Given the
remarkable success of its therapeutic inhibition in psoriasis, the pathogenic role of this�…

IL-35 downregulates Th17 cell development and suppresses certain types of autoimmune
inflammation such as collagen-induced arthritis and experimental autoimmune uveitis�…