[HTML][HTML] Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
L Wang, B Wang, C Wu, J Wang, M Sun�- International journal of�…, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism�…
neurodevelopmental disorder. Over the past two decades, the prevalence of autism�…
[HTML][HTML] mTOR signaling disruption and its association with the development of autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic�…
by impairments in social interaction and communication along with repetitive stereotypic�…
[HTML][HTML] Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of�…
disorders, difficult to diagnose and currently lacking treatment options. The possibility of�…
[HTML][HTML] Inflammatory mediators drive neuroinflammation in autism spectrum disorder and cerebral palsy
UTT Than, LT Nguyen, PH Nguyen, XH Nguyen…�- Scientific Reports, 2023 - nature.com
Inflammation conditions are associated with autism spectrum disorder (ASD) and cerebral
palsy (CP), primarily observed in the peripheral immune system. However, the extent of�…
palsy (CP), primarily observed in the peripheral immune system. However, the extent of�…
[HTML][HTML] Autistic spectrum disorder (ASD)–Gene, molecular and pathway signatures linking systemic inflammation, mitochondrial dysfunction, transsynaptic signalling�…
Background Despite advances in autism spectrum disorder (ASD) research and the vast
genomic, transcriptomic, and proteomic data available, there are still controversies�…
genomic, transcriptomic, and proteomic data available, there are still controversies�…
[HTML][HTML] Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: A systematic review and meta-analysis
M Ding, S Shi, S Qie, J Li, X Xi�- Frontiers in pediatrics, 2023 - frontiersin.org
Background Studies have found that toxic heavy metals exposure could induce the
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might be�…
generation of reactive oxygen species (ROS), and is of epigenetic effect, which might be�…
[HTML][HTML] Dendritic spine and synapse pathology in chromatin modifier-associated autism spectrum disorders and intellectual disability
Formation of dendritic spine and synapse is an essential final step of brain wiring to
establish functional communication in the developing brain. Recent findings have displayed�…
establish functional communication in the developing brain. Recent findings have displayed�…
[HTML][HTML] Role of gastrointestinal health in managing children with autism spectrum disorder
M Al-Beltagi, NK Saeed, AS Bediwy…�- World journal of�…, 2023 - ncbi.nlm.nih.gov
Children with autism spectrum disorders (ASD) or autism are more prone to gastrointestinal
(GI) disorders than the general population. These disorders can significantly affect their�…
(GI) disorders than the general population. These disorders can significantly affect their�…
Gestational hypothyroxinemia induces ASD-like phenotypes in behavior, proinflammatory markers, and glutamatergic protein expression in mouse offspring of both�…
E Gonz�lez-Madrid, MA Rangel-Ram�rez…�- Frontiers in�…, 2024 - frontiersin.org
Background The prevalence of autism spectrum disorder (ASD) has significantly risen in the
past three decades, prompting researchers to explore the potential contributions of�…
past three decades, prompting researchers to explore the potential contributions of�…
Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: prenatal lysophosphatidylinositol attenuates valproic�…
Abstract Aims Dysregulation of PI3K/Akt/GSK3β signaling has been implicated in various
neurological disorders, including autism spectrum disorder (ASD). G protein-coupled�…
neurological disorders, including autism spectrum disorder (ASD). G protein-coupled�…