Parkinson's disease (PD) is a neurodegenerative disorder characterized by a range of motor
symptoms. Treatments are focused on dopamine replacement therapy or deep brain�…

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for the
motor symptoms of Parkinson's disease (PD). However, the neural elements mediating�…

The subthalamic nucleus (STN) is critical for the execution of intended movements. Loss of
its normal function is strongly associated with several movement disorders, including�…

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an FDA approved, widely
applied therapeutic option for patients with Parkinson's Disease (PD) who suffer from on/off�…

BACKGROUND: The inhibition of neuronal activity by electrical deep brain stimulation is one
of the mechanisms explaining the therapeutic effects in patients with Parkinson disease (PD)�…

Deep brain stimulation (DBS) of the subthalamic nucleus is a symptomatic treatment of
Parkinson's disease but benefits only to a minority of patients due to stringent eligibility�…

The subthalamic nucleus (STN) is a common target for deep brain stimulation (DBS)
treatments of Parkinsonian motor symptoms. According to the dominant model, the STN�…

Abnormal subthalamic nucleus (STN) activity is linked to impaired movement in Parkinson's
disease (PD). The autonomous firing of STN neurons, which contributes to their tonic�…

Background: The inhibition of neuronal activity by electrical deep brain stimulation is one of
the mechanisms explaining the amelioration of levodopa-induced dyskinesia. However�…

Electrical deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective for
ameliorating the motor symptoms of Parkinson's disease (PD) including bradykinesia. The�…