The dorsolateral striatum (DLS) is essential for motor and procedure learning, but the role of
DLS spiny projection neurons (SPNs) of direct and indirect pathways, as marked�…

The dorsal striatum is critically involved in a variety of motor behaviours, including regulation
of motor activity, motor skill learning and motor response to psychostimulant and neuroleptic�…

Motor skill learning requires the activity of the dorsal striatum, with a differential global
implication of the dorsomedial and dorsolateral territories. We investigate here whether and�…

Hypotheses of striatal orchestration of behavior ascribe distinct functions to striatal
subregions, with the dorsolateral striatum (DLS) especially implicated in habitual and skilled�…

The primary motor cortex (M1) and the dorsal striatum play a critical role in motor learning
and the retention of learned behaviors. Motor representations of corticostriatal ensembles�…

In current models, learning the relationship between environmental stimuli and the
outcomes of actions involves both stimulus-driven and goal-directed systems, mediated in�…

Growing evidence supports a critical role for the dorsal striatum in cognitive as well as motor
control. Both lesions and in vivo recordings demonstrate a transition in the engaged dorsal�…

The posterior dorsomedial striatum (pDMS) is mainly composed of medium spiny neurons
(MSNs) expressing either dopamine D1 receptors (D1Rs) or D2Rs. Activation of these two�…

Action control is a key brain function determining the survival of animals in their
environment. In mammals, neurons expressing dopamine D2 receptors (D2R) in the dorsal�…

A cortical-basal ganglia network involving, particularly, the posterior region of dorsomedial
striatum (DMS) has been implicated in the acquisition of goal-directed actions; however, no�…