[HTML][HTML] Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation�…
abnormalities in a variety of spatially diverse brain regions. However, the correlation�…
[HTML][HTML] Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies�…
remains unresolved. This is in part due to small sample sizes of neuroimaging studies�…
Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder
Major depressive disorder emerges from the complex interactions of biological systems that
span genes and molecules through cells, networks, and behavior. Establishing how�…
span genes and molecules through cells, networks, and behavior. Establishing how�…
[HTML][HTML] Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive�…
The neuro-anatomical substrates of major depressive disorder (MDD) are still not well
understood, despite many neuroimaging studies over the past few decades. Here we�…
understood, despite many neuroimaging studies over the past few decades. Here we�…
Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder
Major depressive disorder (MDD) is associated to affected brain wiring. Little is known
whether these changes are stable over time and hence might represent a biological�…
whether these changes are stable over time and hence might represent a biological�…
Neurophysiological stratification of major depressive disorder by distinct trajectories
Major depressive disorder (MDD) has been characterized by structural abnormalities of
multiple brain regions. Nevertheless, little is known about the underlying neuropathological�…
multiple brain regions. Nevertheless, little is known about the underlying neuropathological�…
[HTML][HTML] Regional gene expression signatures are associated with sex-specific functional connectivity changes in depression
The neural substrates of depression may differ in men and women, but the underlying
mechanisms are incompletely understood. Here, we show that depression is associated with�…
mechanisms are incompletely understood. Here, we show that depression is associated with�…
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes
Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal�…
and higher-order cognitive processing. Connectome studies have suggested a principal�…
Subcortical shape alterations in major depressive disorder: Findings from the ENIGMA major depressive disorder working group
Alterations in regional subcortical brain volumes have been investigated as part of the efforts
of an international consortium, ENIGMA, to identify reliable neural correlates of major�…
of an international consortium, ENIGMA, to identify reliable neural correlates of major�…
Anomalous gray matter structural networks in major depressive disorder
Background Major depressive disorder (MDD) is characterized by abnormalities in structure,
function, and connectivity in several brain regions. Few studies have examined how these�…
function, and connectivity in several brain regions. Few studies have examined how these�…