Reward information is represented by many subcortical areas and neuron types, which
constitute a complex network. Its output is usually mediated by the basal ganglia where�…

The fundamental biological importance of rewards has created an increasing interest in the
neuronal processing of reward information. The suggestion that the mechanisms underlying�…

Dopamine projections from the midbrain to striatum and frontal cortex play a major role in
behavioral reactions controlled by rewards. Recent experiments have shown that dopamine�…

Reward information is processed in a limited number of brain structures, including fronto-
basal ganglia systems. Dopamine neurons respond phasically to primary rewards and�…

Impaired neurotransmission of dopamine neurons projecting from the ventroanterior
midbrain to the striatum and frontal cortex results in a multitude of severe behavioral�…

The brain contains multiple yet distinct systems involved in reward prediction. To understand
the nature of these processes, we recorded single-unit activity from the lateral prefrontal�…

Besides their fundamental movement function evidenced by Parkinsonian deficits, the basal
ganglia are involved in processing closely linked non-motor, cognitive and reward�…

Information related to rewards is processed by a limited number of brain structures. Recent
studies have demonstrated that dopamine neurons respond to appetitive events, such as�…

Recent neurophysiological studies reveal that neurons in certain brain structures carry
specific signals about past and future rewards. Dopamine neurons display a short-latency�…

The prefrontal cortex is involved in acquiring and maintaining information about context,
including the set of task instructions and/or the outcome of previous stimulus–response�…