Autism genetics: opportunities and challenges for clinical translation
Genetic studies have revealed the involvement of hundreds of gene variants in autism. Their
risk effects are highly variable, and they are frequently related to other conditions besides�…
risk effects are highly variable, and they are frequently related to other conditions besides�…
Gene expression studies in autism: moving from the genome to the transcriptome and beyond
I Voineagu�- Neurobiology of disease, 2012 - Elsevier
Autism is a clinically and genetically heterogeneous neurodevelopmental disorder. Although
multiple genes, risk alleles and copy number variants (CNVs) have been implicated in ASD�…
multiple genes, risk alleles and copy number variants (CNVs) have been implicated in ASD�…
[HTML][HTML] Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
Autism spectrum disorder (ASD) is a phenotypically and genetically heterogeneous
neurodevelopmental disorder. Despite this heterogeneity, previous studies have shown�…
neurodevelopmental disorder. Despite this heterogeneity, previous studies have shown�…
[HTML][HTML] Clinical genetics evaluation in identifying the etiology of autism spectrum disorders: 2013 guideline revisions
GB Schaefer, NJ Mendelsohn…�- Genetics in�…, 2013 - Elsevier
The autism spectrum disorders are a collective of conditions that have in common impaired
socialization and communication in association with stereotypic behaviors. The reported�…
socialization and communication in association with stereotypic behaviors. The reported�…
[PDF][PDF] Autism spectrum disorder-a complex genetic disorder
Р Комплексное, Г ЗАБОЛЕВАНИЕ�- Folia medica, 2015 - archive.sciendo.com
Autism spectrum disorder is an entity that reflects a scientific consensus that several
previously separated disorders are actually a single spectrum disorder with different levels�…
previously separated disorders are actually a single spectrum disorder with different levels�…
Key role for gene dosage and synaptic homeostasis in autism spectrum disorders
Autism spectrum disorders (ASD) are characterized by impairments in reciprocal social
communication, and repetitive, stereotyped verbal and non-verbal behaviors. Genetic�…
communication, and repetitive, stereotyped verbal and non-verbal behaviors. Genetic�…
[HTML][HTML] Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders
Abstract Background Autism spectrum disorders (ASDs) comprise a range of
neurodevelopmental conditions of varying severity, characterized by marked qualitative�…
neurodevelopmental conditions of varying severity, characterized by marked qualitative�…
A review of gene linkage, association and expression studies in autism and an assessment of convergent evidence
MS Yang, M Gill�- International Journal of Developmental Neuroscience, 2007 - Elsevier
Autism is a neurodevelopmental disorder with high heritability and a likely complex genetic
architecture. Much genetic evidence has accumulated in the last 20 years but no gene has�…
architecture. Much genetic evidence has accumulated in the last 20 years but no gene has�…
[BOOK][B] International handbook of autism and pervasive developmental disorders
JL Matson, P Sturmey - 2011 - books.google.com
Since the early 1940s, when first identified as childhood psychosis and autistic psychopathy,
autism spectrum disorder (ASD) has continued to burgeon into a major focus of inquiry and�…
autism spectrum disorder (ASD) has continued to burgeon into a major focus of inquiry and�…
[HTML][HTML] The role of epigenetic change in autism spectrum disorders
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and�…
disorders characterized by problems with social communication, social interaction, and�…