The genetic and phenotypic heterogeneity of autism spectrum disorders (ASD) presents a
substantial challenge for diagnosis, classification, research, and treatment. Investigations�…

Background An emerging literature on behavioural phenotypes has highlighted apparent
associations between autism spectrum disorders (ASDs) or ASD‐related phenomenology�…

Recent progress in the identification of genes and genomic regions contributing to autism
spectrum disorder (ASD) has had a broad impact on our understanding of the nature of�…

The extreme genetic heterogeneity of autism spectrum disorder (ASD) represents a major
challenge. Recent advances in genetic screening and systems biology approaches have�…

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly�…

Autism spectrum disorder is a neurodevelopmental disorder characterized by deficits in
communication, stereotyped behaviors, restricted interests, and impaired social skills. The�…

Background Autism is a common neurodevelopmental syndrome. Numerous rare genetic
etiologies are reported; most cases are idiopathic. Methodology/Principal Findings To�…

Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An�…

Autism is a heterogeneous syndrome defined by impairments in three core domains: social
interaction, language and range of interests. Recent work has led to the identification of�…

OBJECTIVE: Current research suggests that the causes of autism spectrum disorders (ASD)
are multifactorial and include both genetic and environmental factors. Several lines of�…