Cognitive impairment following high fat diet consumption is associated with brain inflammation
PJ Pistell, CD Morrison, S Gupta, AG Knight…�- Journal of�…, 2010 - Elsevier
C57Bl/6 mice were administered a high fat, Western diet (WD, 41% fat) or a very high fat lard
diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for�…
diet (HFL, 60% fat), and evaluated for cognitive ability using the Stone T-maze and for�…
[HTML][HTML] High-fat diet feeding differentially affects the development of inflammation in the central nervous system
O Guillemot-Legris, J Masquelier, A Everard…�- Journal of�…, 2016 - Springer
Background Obesity and its associated disorders are becoming a major health issue in
many countries. The resulting low-grade inflammation not only affects the periphery but also�…
many countries. The resulting low-grade inflammation not only affects the periphery but also�…
Fasting Induces an Anti‐Inflammatory Effect on the Neuroimmune System Which a High‐Fat Diet Prevents
DN Lavin, JJ Joesting, GS Chiu, ML Moon, J Meng…�- …, 2011 - Wiley Online Library
The neuroimmunological and behavioral consequences of a high‐fat diet (HFD) are not well
delineated. This is especially true when short term (24 h) fasting is used as a physiologic�…
delineated. This is especially true when short term (24 h) fasting is used as a physiologic�…
The effects of dietary saturated fat on basal hypothalamic neuroinflammation in rats
T Maric, B Woodside, GN Luheshi�- Brain, behavior, and immunity, 2014 - Elsevier
Recent evidence has demonstrated that consumption of high fat diets can trigger brain
inflammation and subsequent injury in the absence of any peripheral inflammatory�…
inflammation and subsequent injury in the absence of any peripheral inflammatory�…
Long-term high-fat diet consumption by mice throughout adulthood induces neurobehavioral alterations and hippocampal neuronal remodeling accompanied by�…
H Zhuang, X Yao, H Li, Q Li, C Yang, C Wang…�- Brain, behavior, and�…, 2022 - Elsevier
High-fat diet (HFD) consumption is generally associated with an increased risk of cognitive
and emotional dysfunctions that constitute a sizeable worldwide health burden with�…
and emotional dysfunctions that constitute a sizeable worldwide health burden with�…
Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein‐positive cells and microglia in male mice
In humans, obesity is associated with brain inflammation, glial reactivity, and immune cells
infiltration. Studies in rodents have shown that glial reactivity occurs within 24 hr of high‐fat�…
infiltration. Studies in rodents have shown that glial reactivity occurs within 24 hr of high‐fat�…
Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions
CP Almeida-Suhett, A Graham, Y Chen, P Deuster�- Physiology & behavior, 2017 - Elsevier
Abstract High-fat diet (HFD)-induced obesity is associated with not only increased risk of
metabolic and cardiovascular diseases, but cognitive deficit, depression and anxiety�…
metabolic and cardiovascular diseases, but cognitive deficit, depression and anxiety�…
High fat diet and its effects on cognitive health: alterations of neuronal and vascular components of brain
S Sharma�- Physiology & Behavior, 2021 - Elsevier
It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and�…
development of metabolic disorders such as type 2 diabetes mellitus, obesity and�…
[HTML][HTML] Neurochemical modifications in the hippocampus, cortex and hypothalamus of mice exposed to long-term high-fat diet
Metabolic syndrome and diabetes impact brain function and metabolism. While it is well
established that rodents exposed to diets rich in saturated fat develop brain dysfunction�…
established that rodents exposed to diets rich in saturated fat develop brain dysfunction�…
[HTML][HTML] High-fat diet enhances working memory in the Y-maze test in male C57BL/6J mice with less anxiety in the elevated plus maze test
K Yoshizaki, M Asai, T Hara�- Nutrients, 2020 - mdpi.com
Obesity is characterized by massive adipose tissue accumulation and is associated with
psychiatric disorders and cognitive impairment in human and animal models. However, it is�…
psychiatric disorders and cognitive impairment in human and animal models. However, it is�…