Cognitive deficits in fragile X syndrome (FXS) are attributed to molecular abnormalities of the
brain's vast and heterogeneous synapse populations. Unfortunately, the density of synapses�…

Fragile X syndrome (FXS) is the most common cause of heritable intellectual disability and
autism and affects~ 1 in 4000 males and 1 in 8000 females. The discovery of effective�…

Proper brain function requires stringent balance of excitatory and inhibitory synapse
formation during neural circuit assembly. Mutation of genes that normally sculpt and�…

Fragile X syndrome (FXS), the most common cause of inherited mental retardation, is
caused by the loss of the mRNA binding protein, FMRP. Persons with FXS also display�…

Fragile X syndrome (FXS) is the most frequent inherited form of human mental retardation. It
is characterized by cognitive impairment and physical and behavioral problems and is�…

Fragile X syndrome (FXS) is the leading genetic cause of autism spectrum disorder (ASD)
and inherited intellectual disability (ID) worldwide. Preclinical successes in understanding�…

FXS (Fragile X syndrome) is the most common genetically inherited form of cognitive
impairment. The predominant cause of the syndrome is the loss of a single protein, FMRP�…

Epigenetic silencing of fragile X mental retardation 1 (FMR1) causes fragile X syndrome
(FXS), a common inherited form of intellectual disability and autism. FXS correlates with�…

Fragile X syndrome (FXS) is a common inherited form of mental retardation that is caused, in
the vast majority of cases, by the transcriptional silencing of a single gene, fmr1. The�…

The fragile X mental retardation 1 gene (FMR1) mutation causes two disorders: fragile X
syndrome (FXS) in those with the full mutation and the fragile X-associated tremor/ataxia�…