Fragile X syndrome (FXS) is an inherited neurodevelopmental disease caused by loss of
function of the fragile X mental retardation protein (FMRP). In the absence of FMRP�…

Abstract Background Fragile X Syndrome (FXS) is the most common monogenic form of
intellectual disability and one of the few known monogenic causes of autism. It is caused by�…

Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the
best-described monogenic cause of autism. CGG-repeat expansion in the FMR1 gene leads�…

Individuals affected by Fragile X syndrome (FXS) experience cognitive impairment,
hyperactivity, attention deficits, social anxiety and autistic-like behaviors. FXS results from�…

Fragile X syndrome (FXS), the most prevalent heritable form of intellectual disability, is
caused by the transcriptional silencing of the FMR1 gene. While neuronal contribution to�…

Fragile X syndrome (FXS) is the most common inherited intellectual disability. FXS results
from a mutation that causes silencing of the FMR1 gene, which encodes the fragile X mental�…

Fragile X syndrome (FXS)–the leading cause of inherited mental retardation–is an X-linked
disease caused by loss of expression of the FMR1 (fragile X mental retardation 1) gene. In�…

Many clinical and molecular features of the fragile X syndrome, a common form of
intellectual disability and autism, can be modeled by deletion of the Fmr1 protein (Fmrp) in�…

Abstract Background Fragile X syndrome (FXS), the most common genetic cause of autism
spectrum disorder and intellectual disability, is caused by the lack of fragile X mental�…

Silencing of a single gene, FMR1, is linked to a highly prevalent form of mental retardation,
characterized by social and cognitive impairments, known as fragile X syndrome (FXS). The�…