Impaired inhibitory control of cortical synchronization in fragile X syndrome
SM Paluszkiewicz, JL Olmos-Serrano…�- Journal of�…, 2011 - journals.physiology.org
Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by severe
cognitive impairments, sensory hypersensitivity, and comorbidities with autism and epilepsy�…
cognitive impairments, sensory hypersensitivity, and comorbidities with autism and epilepsy�…
Multifarious functions of the fragile X mental retardation protein
JK Davis, K Broadie�- Trends in Genetics, 2017 - cell.com
Fragile X syndrome (FXS), a heritable intellectual and autism spectrum disorder (ASD),
results from the loss of Fragile X mental retardation protein (FMRP). This�…
results from the loss of Fragile X mental retardation protein (FMRP). This�…
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation
BE Pfeiffer, KM Huber�- Journal of neuroscience, 2007 - Soc Neuroscience
Fragile X syndrome, as well as other forms of mental retardation and autism, is associated
with altered dendritic spine number and structure. Fragile X syndrome is caused by loss-of�…
with altered dendritic spine number and structure. Fragile X syndrome is caused by loss-of�…
Metabotropic Glutamate Receptor–Mediated Use–Dependent Down-Regulation of Synaptic Excitability Involves the Fragile X Mental Retardation Protein
S Repicky, K Broadie�- Journal of neurophysiology, 2009 - journals.physiology.org
Loss of the mRNA-binding protein FMRP results in the most common inherited form of both
mental retardation and autism spectrum disorders: fragile X syndrome (FXS). The leading�…
mental retardation and autism spectrum disorders: fragile X syndrome (FXS). The leading�…
[HTML][HTML] Hyperexcitability and homeostasis in fragile X syndrome
Fragile X Syndrome (FXS) is a leading inherited cause of autism and intellectual disability,
resulting from a mutation in the FMR1 gene and subsequent loss of its protein product�…
resulting from a mutation in the FMR1 gene and subsequent loss of its protein product�…
[HTML][HTML] Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2
BE Pfeiffer, T Zang, JR Wilkerson, M Taniguchi…�- Neuron, 2010 - cell.com
Fragile X syndrome (FXS), the most common genetic form of mental retardation and autism,
is caused by loss-of-function mutations in an RNA-binding protein, Fragile X Mental�…
is caused by loss-of-function mutations in an RNA-binding protein, Fragile X Mental�…
Fragile X mice: Reduced long‐term potentiation and N‐Methyl‐D‐Aspartate receptor‐mediated neurotransmission in dentate gyrus
SH Yun, BL Trommer�- Journal of neuroscience research, 2011 - Wiley Online Library
Fragile X syndrome (FXS) is a monogenic mental retardation syndrome that frequently
includes autism. The Fmr1‐knockout (Fmr1‐KO) mouse, like FXS‐affected individuals, lacks�…
includes autism. The Fmr1‐knockout (Fmr1‐KO) mouse, like FXS‐affected individuals, lacks�…
Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures
LK Myrick, PY Deng, H Hashimoto…�- Proceedings of the�…, 2015 - National Acad Sciences
Fragile X syndrome (FXS) results in intellectual disability (ID) most often caused by silencing
of the fragile X mental retardation 1 (FMR1) gene. The resulting absence of fragile X mental�…
of the fragile X mental retardation 1 (FMR1) gene. The resulting absence of fragile X mental�…
GABAergic circuit dysfunction in the Drosophila Fragile X syndrome model
CL Gatto, D Pereira, K Broadie�- Neurobiology of disease, 2014 - Elsevier
Fragile X syndrome (FXS), caused by loss of FMR1 gene function, is the most common
heritable cause of intellectual disability and autism spectrum disorders. The FMR1 protein�…
heritable cause of intellectual disability and autism spectrum disorders. The FMR1 protein�…
Fragile X syndrome
RJ Hagerman, E Berry-Kravis, HC Hazlett…�- Nature reviews Disease�…, 2017 - nature.com
Fragile X syndrome (FXS) is the leading inherited form of intellectual disability and autism
spectrum disorder, and patients can present with severe behavioural alterations, including�…
spectrum disorder, and patients can present with severe behavioural alterations, including�…