Autism is a behaviorally defined, life‐long static developmental disorder of the brain that is
poised for neurobiological investigation. It affects at least 1 or 2 in 1000 persons and has a�…

Autism, used here as short for autism spectrum disorders (ASDs), is not a disease as it does
not have a unique biologic cause. It is a behaviorally defined syndrome of early life, with�…

Publisher Summary This chapter discusses neurobiological studies and reviews the
diseases associated with autism. Genetic research becomes a major focus in studying the�…

Early infantile autism is the most severe of a group of neurodevelopmental syndromes called
the pervasive developmental disorders. The clinical features of autism vary greatly, but, by�…

A review of the neuropathology of infantile autism shows abnormalities in the limbic
forebrain and in cerebellar circuits. The role of the cerebellar lesions in the symptomatology�…

The neuropathology of infantile autism has been reviewed in several recent publications. 1,
2 We have examined the whole brain serial sections of nine well documented cases of�…

A new neurobiological phenomenon in autism has been described that precedes the onset
of clinical behavioral symptoms, and is brief and age-delimited to the first two years of life�…

Infantile autism, a behaviorally defined disorder initially described by Kanner (1), is a
syndrome which, by definition, is manifested by 36 months of age and is characterized by�…

Autism is a behaviourally defined disorder, initially described by Kanner in 1943. By
definition, symptoms are manifested by 36 months of age and are characterized by delayed�…

• We analyze the behavioral and motor disturbances in childhood autism. On the basis of
analogy to signs and conditions seen in adult neurology, we propose that the syndrome�…