[HTML][HTML] Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga…�- Signal transduction and�…, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known�…

Autism spectrum disorder: signaling pathways and prospective therapeutic targets

J Baranova, G Dragunas, MCS Botellho…�- Cellular and molecular�…, 2021 - Springer
Abstract The Autism Spectrum Disorder (ASD) consists of a prevalent and heterogeneous
group of neurodevelopmental diseases representing a severe burden to affected individuals�…

[HTML][HTML] Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy

L Wang, B Wang, C Wu, J Wang, M Sun�- International journal of�…, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism�…

[HTML][HTML] Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man�- Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior�…

[HTML][HTML] Genetic causes and modifiers of autism spectrum disorder

L Rylaarsdam, A Guemez-Gamboa�- Frontiers in cellular�…, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous�…

[HTML][HTML] Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk

S Kumar, K Reynolds, Y Ji, R Gu, S Rai…�- Journal of�…, 2019 - Springer
Background The development of an autistic brain is a highly complex process as evident
from the involvement of various genetic and non-genetic factors in the etiology of the autism�…

Overview of the recent advances in pathophysiology and treatment for autism

H Famitafreshi, M Karimian�- CNS & Neurological Disorders�…, 2018 - ingentaconnect.com
Background & Objective: Autism is a developmental disorder that manifests itself in early
childhood. Autism is characterized by inability to acquire social skills, repetitive behaviors�…

[HTML][HTML] Characterizing autism spectrum disorders by key biochemical pathways

M Subramanian, CK Timmerman, JL Schwartz…�- Frontiers in�…, 2015 - frontiersin.org
The genetic and phenotypic heterogeneity of autism spectrum disorders (ASD) presents a
substantial challenge for diagnosis, classification, research, and treatment. Investigations�…

Advances in autism

DH Geschwind�- Annual review of medicine, 2009 - annualreviews.org
Autism is a common childhood neurodevelopmental disorder with strong genetic liability. It is
not a unitary entity but a clinical syndrome, with variable deficits in social behavior and�…

[HTML][HTML] Translational approaches to the biology of Autism: false dawn or a new era?

C Ecker, W Spooren, DGM Murphy�- Molecular psychiatry, 2013 - nature.com
Discovering novel treatments for Autism Spectrum Disorders (ASD) is a challenge. Its
etiology and pathology remain largely unknown, the condition shows wide clinical diversity�…