Estrogens and autoimmune diseases
Sex hormones are implicated in the immune response, with estrogens as enhancers at least
of the humoral immunity and androgens and progesterone (and glucocorticoids) as natural�…
of the humoral immunity and androgens and progesterone (and glucocorticoids) as natural�…
Estrogen metabolism and autoimmunity
Epidemiological and experimental immunological evidence suggest that estrogens enhance
the humoral immune response, and at the same time, seem to play important roles in�…
the humoral immune response, and at the same time, seem to play important roles in�…
Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity
Sex hormones seem to play an important role as modulators of the autoimmune disease
onset/perpetuation. Generally, steroid hormones are implicated in the immune response�…
onset/perpetuation. Generally, steroid hormones are implicated in the immune response�…
Increased estrogen formation and estrogen to androgen ratio in the synovial fluid of patients with rheumatoid arthritis.
LA Castagnetta, G Carruba, OM Granata…�- The Journal of�…, 2003 - jrheum.org
OBJECTIVE: It has been proposed that physiologic levels of estrogens stimulate immune
responses whereas androgens suppress inflammatory reactions. Thus, prevalence of�…
responses whereas androgens suppress inflammatory reactions. Thus, prevalence of�…
Synovial fluid estrogens in rheumatoid arthritis
M Cutolo, B Villaggio, B Seriolo, P Montagna…�- Autoimmunity�…, 2004 - Elsevier
Experimental and clinical evidence suggest that immune reactivity is modulated by gender.
Immune reactivity is greater in females than in males and lymphocytes and monocytes from�…
Immune reactivity is greater in females than in males and lymphocytes and monocytes from�…
Sex hormones and rheumatoid arthritis
M Cutolo, B Villaggio, C Craviotto, C Pizzorni…�- Autoimmunity�…, 2002 - Elsevier
Sex hormones are implicated in the immune response, with estrogens as enhancers at least
of the humoral immunity and androgens and progesterone as natural immune-suppressors�…
of the humoral immunity and androgens and progesterone as natural immune-suppressors�…
Androgens and estrogens modulate the immune and inflammatory responses in rheumatoid arthritis
M Cutolo, B Seriolo, B Villaggio…�- Annals of the New�…, 2002 - Wiley Online Library
Generally, androgens exert suppressive effects on both humoral and cellular immune
responses and seem to represent natural anti‐inflammatory hormones; in contrast�…
responses and seem to represent natural anti‐inflammatory hormones; in contrast�…
The immunomodulatory effects of estrogens: clinical relevance in immune‐mediated rheumatic diseases
M Cutolo, R Brizzolara, F Atzeni…�- Annals of the New�…, 2010 - Wiley Online Library
Immunological, epidemiological, and clinical evidence suggest that female sex hormones
play an important role in the etiology and pathophysiology of chronic immune/inflammatory�…
play an important role in the etiology and pathophysiology of chronic immune/inflammatory�…
Sex hormones and autoimmunity
DA Gonz�lez, BB D�az, MCR P�rez, AG Hern�ndez…�- Immunology letters, 2010 - Elsevier
Autoimmune diseases occur more in women than in men, and this may be attributable to the
role of estrogens. Androgens promote autoimmune diseases with a profile of type 1�…
role of estrogens. Androgens promote autoimmune diseases with a profile of type 1�…
Estrogen-mediated immunosuppression in autoimmune diseases
L Jansson, R Holmdahl�- Inflammation research, 1998 - Springer
Gender affects the susceptibility to many autoimmune diseases. Women have an increased
risk of developing diseases such as rheumatoid arthritis and multiple sclerosis compared�…
risk of developing diseases such as rheumatoid arthritis and multiple sclerosis compared�…
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