Autism: maternally derived antibodies specific for fetal brain proteins
D Braunschweig, P Ashwood, P Krakowiak…�- Neurotoxicology, 2008 - Elsevier
Autism is a profound disorder of neurodevelopment with poorly understood biological
origins. A potential role for maternal autoantibodies in the etiology of some cases of autism�…
origins. A potential role for maternal autoantibodies in the etiology of some cases of autism�…
Maternal antibrain antibodies in autism
AW Zimmerman, SL Connors, KJ Matteson…�- Brain, behavior, and�…, 2007 - Elsevier
Autism is a neurodevelopmental disorder of prenatal onset that is behaviorally defined.
There is increasing evidence for systemic and neuroimmune mechanisms in children with�…
There is increasing evidence for systemic and neuroimmune mechanisms in children with�…
Antibodies against fetal brain in sera of mothers with autistic children
Serum antibodies in 100 mothers of children with autistic disorder (MCAD) were compared
to 100 age-matched mothers with unaffected children (MUC) using as antigenic substrates�…
to 100 age-matched mothers with unaffected children (MUC) using as antigenic substrates�…
Maternal mid-pregnancy autoantibodies to fetal brain protein: the early markers for autism study
LA Croen, D Braunschweig, L Haapanen…�- Biological�…, 2008 - Elsevier
BACKGROUND: Immune dysfunction has been associated with autism, yet whether
maternal immune status during pregnancy plays a causal role remains to be clarified�…
maternal immune status during pregnancy plays a causal role remains to be clarified�…
Autoantibodies to cerebellum in children with autism associate with behavior
P Goines, L Haapanen, R Boyce, P Duncanson…�- Brain, behavior, and�…, 2011 - Elsevier
Autism is a heterogeneous disorder with a poorly understood biological basis. Some
children with autism harbor plasma autoantibodies that target brain proteins. Similarly, some�…
children with autism harbor plasma autoantibodies that target brain proteins. Similarly, some�…
Behavioral correlates of maternal antibody status among children with autism
D Braunschweig, P Duncanson, R Boyce…�- Journal of autism and�…, 2012 - Springer
Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United
States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of�…
States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of�…
[HTML][HTML] Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey
Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…
Prenatal exposure to autism-specific maternal autoantibodies alters proliferation of cortical neural precursor cells, enlarges brain, and increases neuronal size in adult�…
V Mart�nez-Cerde�o, J Camacho, E Fox, E Miller…�- Cerebral�…, 2016 - academic.oup.com
Autism spectrum disorders (ASDs) affect up to 1 in 68 children. Autism-specific
autoantibodies directed against fetal brain proteins have been found exclusively in a�…
autoantibodies directed against fetal brain proteins have been found exclusively in a�…
Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder
L Brimberg, A Sadiq, PK Gregersen, B Diamond�- Molecular psychiatry, 2013 - nature.com
It is believed that in utero environmental factors contribute to autism spectrum disorder
(ASD). The goal of this study was to demonstrate, using the largest cohort reported so far�…
(ASD). The goal of this study was to demonstrate, using the largest cohort reported so far�…
Maternal and fetal antibrain antibodies in development and disease
E Fox, D Amaral, J Van de Water�- Developmental�…, 2012 - Wiley Online Library
Recent evidence has emerged indicating that the maternal immune response can have a
substantial deleterious impact on prenatal development (Croen et al.,[2008]: Biol Psychiatry�…
substantial deleterious impact on prenatal development (Croen et al.,[2008]: Biol Psychiatry�…