Serum antibodies in 100 mothers of children with autistic disorder (MCAD) were compared
to 100 age-matched mothers with unaffected children (MUC) using as antigenic substrates�…

Autism is a neurodevelopmental disorder of prenatal onset that is behaviorally defined.
There is increasing evidence for systemic and neuroimmune mechanisms in children with�…

Autism is a profound disorder of neurodevelopment with poorly understood biological
origins. A potential role for maternal autoantibodies in the etiology of some cases of autism�…

Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…

BACKGROUND: Immune dysfunction has been associated with autism, yet whether
maternal immune status during pregnancy plays a causal role remains to be clarified�…

It is believed that in utero environmental factors contribute to autism spectrum disorder
(ASD). The goal of this study was to demonstrate, using the largest cohort reported so far�…

Neurodevelopmental disorders could be caused by maternal antibodies or other serum
factors. We detected serum antibodies binding to rodent Purkinje cells and other neurons in�…

Recent evidence has emerged indicating that the maternal immune response can have a
substantial deleterious impact on prenatal development (Croen et al.,[2008]: Biol Psychiatry�…

A pregnant mouse model was used to compare the effect of IgG, administered E13-E18,
from mothers of children with autistic disorder (MCAD), to controls (simple-and IgG-) on�…

Serum autoantibodies to human brain, identified by ELISA and Western immunoblotting,
were evaluated in 29 children with autism spectrum disorder (22 with autistic disorder), 9�…