The genetic architecture of autism spectrum disorder (ASD) is itself a diverse allelic
spectrum that consists of rare de novo or inherited variants in hundreds of genes and�…

Highlights•High throughput genomic methods are rapidly increasing the pool of ASD
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to�…

Autism spectrum disorders (ASD s) are a group of heterogeneous neurodevelopmental
disorders that show impaired communication and socialization, restricted interests, and�…

Autism spectrum disorder (ASD) is a highly heritable, clinically diverse group of
neurodevelopmental disorders. Its genetic heterogeneity is remarkable, with more than 800�…

Characterized by a combination of abnormalities in language, social cognition and mental
flexibility, autism is not a single disorder but a neurodevelopmental syndrome commonly�…

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic
component. Recently developed genomic technologies, including microarray and next�…

Autism spectrum disorder (ASD) is characterized by impairments in reciprocal social
interaction and communication, and by restricted and repetitive behaviors. Family studies�…

The autism spectrum disorders (ASD) are a heterogeneous set of developmental disorders
characterized at their core by deficits in social interaction and communication. Current�…

Autism spectrum disorder (ASD) is a severe neuropsychiatric disease with strong genetic
underpinnings. However, genetic contributions to autism are extremely heterogeneous, with�…

Autism spectrum disorder (ASD) is the term for a range of development disorders caused by
a combination of genetic and environmental factors (Kubota et al., 2012; Loke et al., 2015;�…