Anti-brain antibodies are associated with more severe cognitive and behavioral profiles in Italian children with Autism Spectrum Disorder

IS Piras, L Haapanen, V Napolioni, R Sacco…�- Brain, behavior, and�…, 2014 - Elsevier
Circulating 45 and 62 kDa antibodies targeting the cerebellum were previously associated
with Autism Spectrum Disorder (ASD), lower adaptive/cognitive function and aberrant�…

Maternal immune activation: Implications for neuropsychiatric disorders

ML Estes, AK McAllister�- Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that�…

Immune regulation of neurodevelopment at the mother–foetus interface: the case of autism

S Sotgiu, S Manca, A Gagliano…�- Clinical &�…, 2020 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by deficits in
social communication and stereotypical behaviours. ASD's aetiology remains mostly�…

Autoimmune diseases in parents of children with infantile autism: a case—control study

SE Mouridsen, B Rich, T Isager…�- …�Medicine & Child�…, 2007 - Wiley Online Library
This register study compared the rates and types of autoimmune disease in the parents of
111 patients (82 males, 29 females; mean age at diagnosis 5y 5mo [SD 2y 6mo]) with�…

Immunologic and neurodevelopmental susceptibilities of autism

IN Pessah, RF Seegal, PJ Lein, J LaSalle, BK Yee…�- Neurotoxicology, 2008 - Elsevier
Symposium 5 focused on research approaches that are aimed at understanding common
patterns of immunological and neurological dysfunction contributing to neurodevelopmental�…

Immune system gene dysregulation in autism and schizophrenia

M Michel, MJ Schmidt, K Mirnics�- Developmental neurobiology, 2012 - Wiley Online Library
Gene* environment interactions play critical roles in the emergence of autism and
schizophrenia pathophysiology. In both disorders, recent genetic association studies have�…

The placental interleukin-6 signaling controls fetal brain development and behavior

WL Wu, EY Hsiao, Z Yan, SK Mazmanian…�- Brain, behavior, and�…, 2017 - Elsevier
Epidemiological studies show that maternal immune activation (MIA) during pregnancy is a
risk factor for autism. However, mechanisms for how MIA affects brain development and�…

Neuro-inflammatory mechanisms in developmental disorders associated with intellectual disability and autism spectrum disorder: a neuro-immune perspective

B Di Marco, CM Bonaccorso, E Aloisi…�- CNS & Neurological�…, 2016 - ingentaconnect.com
Intellectual disability (ID) and autism are present in several neurodevelopmental disorders
and are often associated in genetic syndromes, such as Fragile X and Rett syndromes�…

Immune dysregulation in autism spectrum disorder

EY Hsiao�- International review of neurobiology, 2013 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous disorder diagnosed based on
the presence and severity of core abnormalities in social communication and repetitive�…

Long-term altered immune responses following fetal priming in a non-human primate model of maternal immune activation

DR Rose, M Careaga, J Van de Water…�- Brain, behavior, and�…, 2017 - Elsevier
Infection during pregnancy can lead to activation of the maternal immune system and has
been associated with an increased risk of having an offspring later diagnosed with a�…