Maternal and early postnatal immune activation produce dissociable effects on neurotransmission in mPFC–amygdala circuits

Y Li, G Missig, BC Finger, SM Landino…�- Journal of�…, 2018 - Soc Neuroscience
Inflammatory processes may be involved in the pathophysiology of neuropsychiatric
illnesses including autism spectrum disorder (ASD). Evidence from studies in rodents�…

[CITATION][C] Immunodiagnosis and Immunotherapy in Autistic Children a

VK Singh, HH Fudenberg, D Emerson…�- Annals of the New�…, 1988 - Wiley Online Library
The etiology and pathogenesis of the autistic syndrome are not known. On the basis of our
current work with other neuropsychiatric disorders,'.'we hypothesized that autism is a�…

Maternal immune activation leads to activated inflammatory macrophages in offspring

CE Onore, JJ Schwartzer, M Careaga…�- Brain, behavior, and�…, 2014 - Elsevier
Several epidemiological studies have shown an association between infection or
inflammation during pregnancy and increased risk of autism in the child. In addition, animal�…

[HTML][HTML] Maternal and early postnatal immune activation produce sex-specific effects on autism-like behaviors and neuroimmune function in mice

WA Carlezon Jr, W Kim, G Missig, BC Finger…�- Scientific reports, 2019 - nature.com
Increasing evidence suggests a role for inflammation in neuropsychiatric conditions
including autism spectrum disorder (ASD), a neurodevelopmental syndrome with higher�…

Modeling autism-related disorders in mice with maternal immune activation (MIA)

CR Lammert, JR Lukens�- Mouse Models of Innate Immunity: Methods and�…, 2019 - Springer
Autism spectrum disorder (ASD) has emerged as one of the most prevalent and poorly
understood disorders of our time. The etiology of autism currently remains poorly�…

Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders

P Coiro, R Padmashri, A Suresh, E Spartz…�- Brain, behavior, and�…, 2015 - Elsevier
Both genetic and environmental factors are thought to contribute to neurodevelopmental and
neuropsychiatric disorders with maternal immune activation (MIA) being a risk factor for both�…

Genetic and immunologic considerations in autism

E Korvatska, J Van de Water, TF Anders…�- Neurobiology of�…, 2002 - Elsevier
According to recent epidemiological surveys, autistic spectrum disorders have become
recognized as common childhood psychopathologies. These life-lasting conditions�…

Toward an immune-mediated subtype of autism spectrum disorder

CJ McDougle, SM Landino, A Vahabzadeh, J O'Rourke…�- Brain research, 2015 - Elsevier
A role for immunological involvement in autism spectrum disorder (ASD) has long been
hypothesized. This review includes four sections describing (1) evidence for a relationship�…

[HTML][HTML] Maternal autoantibody profiles as biomarkers for ASD and ASD with co-occurring intellectual disability

A Ramirez-Celis, LA Croen, CK Yoshida…�- Molecular�…, 2022 - nature.com
Maternal autoantibody-related ASD (MAR ASD) is a subtype of autism in which pathogenic
maternal autoantibodies (IgG) cross the placenta, access the developing brain, and cause�…

Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms

L Heuer, P Ashwood, J Schauer, P Goines…�- Autism�…, 2008 - Wiley Online Library
Objectives: To assay if plasma antibody levels in children with autism or developmental
delays (DD) differ from those with typical development as an indicator of immune function�…