Maternal and early postnatal immune activation produce dissociable effects on neurotransmission in mPFC–amygdala circuits
Inflammatory processes may be involved in the pathophysiology of neuropsychiatric
illnesses including autism spectrum disorder (ASD). Evidence from studies in rodents�…
illnesses including autism spectrum disorder (ASD). Evidence from studies in rodents�…
[CITATION][C] Immunodiagnosis and Immunotherapy in Autistic Children a
VK Singh, HH Fudenberg, D Emerson…�- Annals of the New�…, 1988 - Wiley Online Library
The etiology and pathogenesis of the autistic syndrome are not known. On the basis of our
current work with other neuropsychiatric disorders,'.'we hypothesized that autism is a�…
current work with other neuropsychiatric disorders,'.'we hypothesized that autism is a�…
Maternal immune activation leads to activated inflammatory macrophages in offspring
CE Onore, JJ Schwartzer, M Careaga…�- Brain, behavior, and�…, 2014 - Elsevier
Several epidemiological studies have shown an association between infection or
inflammation during pregnancy and increased risk of autism in the child. In addition, animal�…
inflammation during pregnancy and increased risk of autism in the child. In addition, animal�…
[HTML][HTML] Maternal and early postnatal immune activation produce sex-specific effects on autism-like behaviors and neuroimmune function in mice
Increasing evidence suggests a role for inflammation in neuropsychiatric conditions
including autism spectrum disorder (ASD), a neurodevelopmental syndrome with higher�…
including autism spectrum disorder (ASD), a neurodevelopmental syndrome with higher�…
Modeling autism-related disorders in mice with maternal immune activation (MIA)
CR Lammert, JR Lukens�- Mouse Models of Innate Immunity: Methods and�…, 2019 - Springer
Autism spectrum disorder (ASD) has emerged as one of the most prevalent and poorly
understood disorders of our time. The etiology of autism currently remains poorly�…
understood disorders of our time. The etiology of autism currently remains poorly�…
Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders
Both genetic and environmental factors are thought to contribute to neurodevelopmental and
neuropsychiatric disorders with maternal immune activation (MIA) being a risk factor for both�…
neuropsychiatric disorders with maternal immune activation (MIA) being a risk factor for both�…
Genetic and immunologic considerations in autism
E Korvatska, J Van de Water, TF Anders…�- Neurobiology of�…, 2002 - Elsevier
According to recent epidemiological surveys, autistic spectrum disorders have become
recognized as common childhood psychopathologies. These life-lasting conditions�…
recognized as common childhood psychopathologies. These life-lasting conditions�…
Toward an immune-mediated subtype of autism spectrum disorder
CJ McDougle, SM Landino, A Vahabzadeh, J O'Rourke…�- Brain research, 2015 - Elsevier
A role for immunological involvement in autism spectrum disorder (ASD) has long been
hypothesized. This review includes four sections describing (1) evidence for a relationship�…
hypothesized. This review includes four sections describing (1) evidence for a relationship�…
[HTML][HTML] Maternal autoantibody profiles as biomarkers for ASD and ASD with co-occurring intellectual disability
A Ramirez-Celis, LA Croen, CK Yoshida…�- Molecular�…, 2022 - nature.com
Maternal autoantibody-related ASD (MAR ASD) is a subtype of autism in which pathogenic
maternal autoantibodies (IgG) cross the placenta, access the developing brain, and cause�…
maternal autoantibodies (IgG) cross the placenta, access the developing brain, and cause�…
Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms
L Heuer, P Ashwood, J Schauer, P Goines…�- Autism�…, 2008 - Wiley Online Library
Objectives: To assay if plasma antibody levels in children with autism or developmental
delays (DD) differ from those with typical development as an indicator of immune function�…
delays (DD) differ from those with typical development as an indicator of immune function�…