The fragile X mental retardation protein (FMRP) is an RNA-binding protein involved in
translational regulation of mRNAs that play key roles in synaptic morphology and plasticity�…

Maternal RNA degradation is critical for embryogenesis and is tightly controlled by maternal
RNA-binding proteins. Fragile X mental-retardation protein (FMR1) binds target mRNAs to�…

Conspectus The development of various chemical methods has enabled scientists to
decipher the distribution features and biological functions of RNA modifications in the past�…

Abstract N 6-methyladenosine (m6A) is the most abundant internal mRNA nucleotide
modification in mammals, regulating critical aspects of cell physiology and differentiation�…

Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A�…

Fragile X syndrome (FXS), caused by the loss of functional FMRP, is a leading cause of
autism. Neurons lacking FMRP show aberrant mRNA translation and intracellular signalling�…

Summary N6-methyladenosine (m 6 A) is the most abundant modification on mRNA and is
implicated in critical roles in development, physiology, and disease. A major limitation has�…

RNA modifications have emerged as an additional layer of regulatory complexity governing
the function of almost all species of RNA. N 6-methyladenosine (m6A), the addition of methyl�…

Abstract N 6-methyladenosine (m6A) and its regulatory components play critical roles in
various developmental processes in mammals. However, the landscape and function of�…

Abstract Background N 6-methyladenosine (m 6 A) is an important epitranscriptomic mark
with high abundance in the brain. Recently, it has been found to be involved in the�…