Visceral pain/discomfort is the cardinal complaints and treatment targets for functional
gastrointestinal disorders (FGID). However, effective treatment for such pain is limited and�…

Objective Understanding the neural circuitry of placebo analgesia in the context of visceral
pain is increasingly important given evidence of clinical benefit of placebo treatment in IBS�…

Background We explored sex differences in the neural mechanisms mediating placebo
analgesia in an established visceral pain model involving painful rectal distensions in�…

This functional magnetic resonance imaging study analysed the behavioural and neural
responses during expectation-mediated placebo analgesia in a rectal pain model in healthy�…

Placebo analgesia is a psychosocial context effect that is rarely studied in visceral pain.
Patients with irritable bowel syndrome (IBS) exhibit visceral hyperalgesia and heightened�…

Background To assess effects of perceived treatment (ie drug vs placebo) on behavioral and
neural responses to rectal pain stimuli delivered in a deceptive placebo condition. Methods�…

To elucidate placebo and nocebo effects in visceral pain, we conducted a functional
magnetic resonance imaging (fMRI) study to analyze effects of positive and negative�…

Two groups of patients with irritable bowel syndrome rated pain and underwent functional
magnetic resonance imaging brain scanning during experimentally induced rectal�…

In the last 10 to 15 years, commonly used neurophysiologic and neuroimaging techniques
have been adapted for use in the human gastrointestinal (GI) tract, rapidly expanding the�…

Previous experiments found that placebos produced small decreases in neural activity of
pain-related areas of the brain, yet decreases were only statistically significant after�…