Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism
LA Martin, P Ashwood, D Braunschweig…�- Brain, behavior, and�…, 2008 - Elsevier
Autism together with Asperger syndrome and pervasive developmental disorder not
otherwise specified form a spectrum of conditions (autism spectrum disorders or ASD) that is�…
otherwise specified form a spectrum of conditions (autism spectrum disorders or ASD) that is�…
Immunological and autoimmune considerations of Autism Spectrum Disorders
Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous
neurodevelopmental conditions presenting in early childhood with a prevalence ranging�…
neurodevelopmental conditions presenting in early childhood with a prevalence ranging�…
Prenatal exposure to antibodies from mothers of children with autism produces neurobehavioral alterations: a pregnant dam mouse model
HS Singer, C Morris, C Gause, M Pollard…�- Journal of�…, 2009 - Elsevier
A pregnant mouse model was used to compare the effect of IgG, administered E13-E18,
from mothers of children with autistic disorder (MCAD), to controls (simple-and IgG-) on�…
from mothers of children with autistic disorder (MCAD), to controls (simple-and IgG-) on�…
[HTML][HTML] Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey
Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…
Maternal autoantibody related autism: mechanisms and pathways
KL Jones, J Van de Water�- Molecular psychiatry, 2019 - nature.com
It has been estimated that autism spectrum disorder (ASD) now affects 1 in 59 children in the
United States. Although the cause (s) of ASD remain largely unknown, it is becoming�…
United States. Although the cause (s) of ASD remain largely unknown, it is becoming�…
Behavioral correlates of maternal antibody status among children with autism
D Braunschweig, P Duncanson, R Boyce…�- Journal of autism and�…, 2012 - Springer
Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United
States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of�…
States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of�…
Maternal autoantibodies are associated with abnormal brain enlargement in a subgroup of children with autism spectrum disorder
Autism spectrum disorder (ASD) is very heterogeneous and multiple subtypes and etiologies
likely exist. The maternal immune system has been implicated in the pathogenesis of some�…
likely exist. The maternal immune system has been implicated in the pathogenesis of some�…
Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model
D Braunschweig, MS Golub, CM Koenig, L Qi…�- Journal of�…, 2012 - Elsevier
A murine passive transfer model system was employed to ascertain the effects of gestational
exposure to a single, intravenous dose of purified, brain-reactive IgG antibodies from�…
exposure to a single, intravenous dose of purified, brain-reactive IgG antibodies from�…
Maternal autoantibodies in autism
D Braunschweig, J Van de Water�- Archives of neurology, 2012 - jamanetwork.com
As epidemiologic studies continue to note a striking increase in rates of autism spectrum
disorder (ASD) diagnosis around the world, the lack of identified causative agents in most�…
disorder (ASD) diagnosis around the world, the lack of identified causative agents in most�…
Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism
KL Jones, MC Pride, E Edmiston, M Yang…�- Molecular�…, 2020 - nature.com
Immune dysregulation has been noted consistently in individuals with autism spectrum
disorder (ASD) and their families, including the presence of autoantibodies reactive to fetal�…
disorder (ASD) and their families, including the presence of autoantibodies reactive to fetal�…