Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism

LA Martin, P Ashwood, D Braunschweig…�- Brain, behavior, and�…, 2008 - Elsevier
Autism together with Asperger syndrome and pervasive developmental disorder not
otherwise specified form a spectrum of conditions (autism spectrum disorders or ASD) that is�…

Immunological and autoimmune considerations of Autism Spectrum Disorders

B Gesundheit, JP Rosenzweig, D Naor, B Lerer…�- Journal of�…, 2013 - Elsevier
Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous
neurodevelopmental conditions presenting in early childhood with a prevalence ranging�…

Prenatal exposure to antibodies from mothers of children with autism produces neurobehavioral alterations: a pregnant dam mouse model

HS Singer, C Morris, C Gause, M Pollard…�- Journal of�…, 2009 - Elsevier
A pregnant mouse model was used to compare the effect of IgG, administered E13-E18,
from mothers of children with autistic disorder (MCAD), to controls (simple-and IgG-) on�…

[HTML][HTML] Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

MD Bauman, AM Iosif, P Ashwood…�- Translational�…, 2013 - nature.com
Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found
in approximately 12% of mothers who have children with autism spectrum disorder (ASD)�…

Maternal autoantibody related autism: mechanisms and pathways

KL Jones, J Van de Water�- Molecular psychiatry, 2019 - nature.com
It has been estimated that autism spectrum disorder (ASD) now affects 1 in 59 children in the
United States. Although the cause (s) of ASD remain largely unknown, it is becoming�…

Behavioral correlates of maternal antibody status among children with autism

D Braunschweig, P Duncanson, R Boyce…�- Journal of autism and�…, 2012 - Springer
Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United
States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of�…

Maternal autoantibodies are associated with abnormal brain enlargement in a subgroup of children with autism spectrum disorder

CW Nordahl, D Braunschweig, AM Iosif, A Lee…�- Brain, behavior, and�…, 2013 - Elsevier
Autism spectrum disorder (ASD) is very heterogeneous and multiple subtypes and etiologies
likely exist. The maternal immune system has been implicated in the pathogenesis of some�…

Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model

D Braunschweig, MS Golub, CM Koenig, L Qi…�- Journal of�…, 2012 - Elsevier
A murine passive transfer model system was employed to ascertain the effects of gestational
exposure to a single, intravenous dose of purified, brain-reactive IgG antibodies from�…

Maternal autoantibodies in autism

D Braunschweig, J Van de Water�- Archives of neurology, 2012 - jamanetwork.com
As epidemiologic studies continue to note a striking increase in rates of autism spectrum
disorder (ASD) diagnosis around the world, the lack of identified causative agents in most�…

Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism

KL Jones, MC Pride, E Edmiston, M Yang…�- Molecular�…, 2020 - nature.com
Immune dysregulation has been noted consistently in individuals with autism spectrum
disorder (ASD) and their families, including the presence of autoantibodies reactive to fetal�…