[HTML][HTML] Clinical and neurobiological relevance of current animal models of autism spectrum disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social
and communication impairments, as well as repetitive and restrictive behaviors. The�…
and communication impairments, as well as repetitive and restrictive behaviors. The�…
Mouse behavior and models for autism spectrum disorders
L Ricceri, C Michetti, ML Scattoni�- Neuronal and synaptic dysfunction in�…, 2016 - Elsevier
Autism spectrum disorders (ASDs) are behaviorally defined disorders including attenuated
or abnormal social interaction and communication, as well as aberrant repetitive behavior�…
or abnormal social interaction and communication, as well as aberrant repetitive behavior�…
Modeling of autism genetic variations in mice: focusing on synaptic and microcircuit dysfunctions
Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental disorders that
are characterized by deficits in social interaction, verbal and nonverbal communication, and�…
are characterized by deficits in social interaction, verbal and nonverbal communication, and�…
[HTML][HTML] Studying autism in rodent models: reconciling endophenotypes with comorbidities
A Argyropoulos, KL Gilby…�- Frontiers in human�…, 2013 - frontiersin.org
Autism spectrum disorder (ASD) patients commonly exhibit a variety of comorbid traits
including seizures, anxiety, aggressive behavior, gastrointestinal problems, motor deficits�…
including seizures, anxiety, aggressive behavior, gastrointestinal problems, motor deficits�…
Genetic animal models for autism spectrum disorder
JC Schroeder, D Reim, TM Boeckers…�- Social behavior from�…, 2017 - Springer
Autism spectrum disorder (ASD) affects approximately 1% of the human population and has
a strong genetic component. Hence, the recent discovery of major “ASD genes” has�…
a strong genetic component. Hence, the recent discovery of major “ASD genes” has�…
Behavioral neuroscience of autism
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models�…
of ASD have been identified and this has enabled researchers to construct mouse models�…
Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches
K Hui, Y Katayama, KI Nakayama, J Nomura…�- Neuroscience &�…, 2020 - Elsevier
Recent human genetics studies have identified many genetic variants that may be
responsible for autism spectrum disorder (ASD). ASD mouse models with genetic�…
responsible for autism spectrum disorder (ASD). ASD mouse models with genetic�…
Leveraging a translational research approach to drive diagnostic and treatment advances for autism
KJ Parker�- Molecular psychiatry, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and poorly understood neurodevelopmental
disorder. There are currently no laboratory-based diagnostic tests to detect ASD, nor are�…
disorder. There are currently no laboratory-based diagnostic tests to detect ASD, nor are�…
Autism spectrum disorders: translating human deficits into mouse behavior
Abstract Autism Spectrum Disorders are a heterogeneous group of neurodevelopmental
disorders, with rising incidence but little effective therapeutic intervention available�…
disorders, with rising incidence but little effective therapeutic intervention available�…
Neurobiological mechanisms of autism spectrum disorder and epilepsy, insights from animal models
T Sierra-Arregui, J Llorente, PG Minguez, J T�nnesen…�- Neuroscience, 2020 - Elsevier
Abstract Autism Spectrum Disorder (ASD) and epilepsy are two neurodevelopmental
disorders that have a high comorbidity rate, suggesting that a common neurodevelopmental�…
disorders that have a high comorbidity rate, suggesting that a common neurodevelopmental�…