Regulatory genes and pathways disrupted in autism spectrum disorders
F Ayhan, G Konopka�- Progress in Neuro-Psychopharmacology and�…, 2019 - Elsevier
Autism spectrum disorder (ASD) is a highly prevalent and complex genetic disorder. The
complex genetic make-up of ASD has been extensively studied and both common and rare�…
complex genetic make-up of ASD has been extensively studied and both common and rare�…
[HTML][HTML] Dissecting the Genetics of Autism Spectrum Disorders: A Drosophila Perspective
P Bellosta, A Soldano�- Frontiers in physiology, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is a complex group of multi-factorial developmental
disorders that leads to communication and behavioral defects. Genetic alterations have�…
disorders that leads to communication and behavioral defects. Genetic alterations have�…
[HTML][HTML] Dopaminergic dysregulation in syndromic autism spectrum disorders: insights from genetic mouse models
Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by altered social
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately�…
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately�…
Genetic advances in autism: heterogeneity and convergence on shared pathways
BR Bill, DH Geschwind�- Current opinion in genetics & development, 2009 - Elsevier
The autism spectrum disorders (ASD) are a heterogeneous set of developmental disorders
characterized at their core by deficits in social interaction and communication. Current�…
characterized at their core by deficits in social interaction and communication. Current�…
Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk
We present the largest exome sequencing study to date focused on rare variation in autism
spectrum disorder (ASD)(n= 35,584). Integrating de novo and case-control variation with an�…
spectrum disorder (ASD)(n= 35,584). Integrating de novo and case-control variation with an�…
Genetic basis of autism: is there a way forward?
V Eapen�- Current opinion in psychiatry, 2011 - journals.lww.com
Understanding the neurobiological processes by which genotypes become phenotypes,
along with the advances in developmental neuroscience and neuronal networks at the�…
along with the advances in developmental neuroscience and neuronal networks at the�…
[HTML][HTML] Epigenetics and autism spectrum disorder: Is there a correlation?
AA Eshraghi, G Liu, SIS Kay, RS Eshraghi…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is the term for a range of development disorders caused by
a combination of genetic and environmental factors (Kubota et al., 2012; Loke et al., 2015;�…
a combination of genetic and environmental factors (Kubota et al., 2012; Loke et al., 2015;�…
Mouse models of autism spectrum disorders: the challenge for behavioral genetics
SS Moy, JJ Nadler, TR Magnuson…�- American Journal of�…, 2006 - Wiley Online Library
Autism is a severe neurodevelopmental disorder, which typically emerges early in
childhood. The core symptoms of autism include deficits in social interaction, impaired�…
childhood. The core symptoms of autism include deficits in social interaction, impaired�…
Autism spectrum disorder genetics: diverse genes with diverse clinical outcomes
ME Talkowski, EV Minikel…�- Harvard review of�…, 2014 - journals.lww.com
The last several years have seen unprecedented advances in deciphering the genetic
etiology of autism spectrum disorders (ASDs). Heritability studies have repeatedly affirmed a�…
etiology of autism spectrum disorders (ASDs). Heritability studies have repeatedly affirmed a�…
Genetic factors and epigenetic factors for autism: endoplasmic reticulum stress and impaired synaptic function
T Momoi, E Fujita, H Senoo…�- Cell biology�…, 2010 - Wiley Online Library
The molecular pathogenesis of ASD (autism spectrum disorder), one of the heritable
neurodevelopmental disorders, is not well understood, although over 15 autistic‐susceptible�…
neurodevelopmental disorders, is not well understood, although over 15 autistic‐susceptible�…