Regulatory genes and pathways disrupted in autism spectrum disorders

F Ayhan, G Konopka�- Progress in Neuro-Psychopharmacology and�…, 2019 - Elsevier
Autism spectrum disorder (ASD) is a highly prevalent and complex genetic disorder. The
complex genetic make-up of ASD has been extensively studied and both common and rare�…

[HTML][HTML] Dissecting the Genetics of Autism Spectrum Disorders: A Drosophila Perspective

P Bellosta, A Soldano�- Frontiers in physiology, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is a complex group of multi-factorial developmental
disorders that leads to communication and behavioral defects. Genetic alterations have�…

[HTML][HTML] Dopaminergic dysregulation in syndromic autism spectrum disorders: insights from genetic mouse models

P Kosillo, HS Bateup�- Frontiers in Neural Circuits, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by altered social
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately�…

Genetic advances in autism: heterogeneity and convergence on shared pathways

BR Bill, DH Geschwind�- Current opinion in genetics & development, 2009 - Elsevier
The autism spectrum disorders (ASD) are a heterogeneous set of developmental disorders
characterized at their core by deficits in social interaction and communication. Current�…

Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk

FK Satterstrom, JA Kosmicki, J Wang, MS Breen…�- BioRxiv, 2018 - biorxiv.org
We present the largest exome sequencing study to date focused on rare variation in autism
spectrum disorder (ASD)(n= 35,584). Integrating de novo and case-control variation with an�…

Genetic basis of autism: is there a way forward?

V Eapen�- Current opinion in psychiatry, 2011 - journals.lww.com
Understanding the neurobiological processes by which genotypes become phenotypes,
along with the advances in developmental neuroscience and neuronal networks at the�…

[HTML][HTML] Epigenetics and autism spectrum disorder: Is there a correlation?

AA Eshraghi, G Liu, SIS Kay, RS Eshraghi…�- Frontiers in cellular�…, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is the term for a range of development disorders caused by
a combination of genetic and environmental factors (Kubota et al., 2012; Loke et al., 2015;�…

Mouse models of autism spectrum disorders: the challenge for behavioral genetics

SS Moy, JJ Nadler, TR Magnuson…�- American Journal of�…, 2006 - Wiley Online Library
Autism is a severe neurodevelopmental disorder, which typically emerges early in
childhood. The core symptoms of autism include deficits in social interaction, impaired�…

Autism spectrum disorder genetics: diverse genes with diverse clinical outcomes

ME Talkowski, EV Minikel…�- Harvard review of�…, 2014 - journals.lww.com
The last several years have seen unprecedented advances in deciphering the genetic
etiology of autism spectrum disorders (ASDs). Heritability studies have repeatedly affirmed a�…

Genetic factors and epigenetic factors for autism: endoplasmic reticulum stress and impaired synaptic function

T Momoi, E Fujita, H Senoo…�- Cell biology�…, 2010 - Wiley Online Library
The molecular pathogenesis of ASD (autism spectrum disorder), one of the heritable
neurodevelopmental disorders, is not well understood, although over 15 autistic‐susceptible�…