[HTML][HTML] Autism spectrum disorder: why do we know so little?
L Emberti Gialloreti, P Curatolo�- Frontiers in neurology, 2018 - frontiersin.org
In the last 50 years, research in Autism Spectrum Disorder (ASD) has constantly grown.
However, etiology and pathogenesis of this disorder are still a matter of speculation. Thus�…
However, etiology and pathogenesis of this disorder are still a matter of speculation. Thus�…
Resolving the synaptic versus developmental dichotomy of autism risk genes
WE Heavner, SEP Smith�- Trends in neurosciences, 2020 - cell.com
Genes that are mutated in Autism Spectrum Disorders (ASD) can be classified broadly as
either synaptic or developmental. But what if this is a false distinction? A recent spate of�…
either synaptic or developmental. But what if this is a false distinction? A recent spate of�…
Genetic modules for autism
B LaFlamme�- Nature Genetics, 2015 - nature.com
Autism spectrum disorder (ASD) is genetically heterogeneous, with most ASD-associated
variants accounting for very few cases. Michael Snyder and colleagues used a systems�…
variants accounting for very few cases. Michael Snyder and colleagues used a systems�…
Neocortical neurogenesis and the etiology of autism spectrum disorder
A Packer�- Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Researchers have now identified many highly penetrant genetic risk factors for autism
spectrum disorder (ASD). Some of these genes encode synaptic proteins, lending support to�…
spectrum disorder (ASD). Some of these genes encode synaptic proteins, lending support to�…
Behavioral profiles of mouse models for autism spectrum disorders
E Ey, CS Leblond, T Bourgeron�- Autism research, 2011 - Wiley Online Library
Autism spectrum disorders (ASD) are characterized by impairments in reciprocal social
communication, and stereotyped verbal and nonverbal behaviors. In approximately 10–25�…
communication, and stereotyped verbal and nonverbal behaviors. In approximately 10–25�…
[HTML][HTML] Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling
M Allen, BS Huang, MJ Notaras, A Lodhi…�- Molecular�…, 2022 - nature.com
The cellular mechanisms of autism spectrum disorder (ASD) are poorly understood.
Cumulative evidence suggests that abnormal synapse function underlies many features of�…
Cumulative evidence suggests that abnormal synapse function underlies many features of�…
Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors
R Bhandari, JK Paliwal, A Kuhad�- …�food intervention and therapy for autism�…, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger�…
development disorders (PDD) which ranges from atypical autism, autism, and Asperger�…
Autism genetics: strategies, challenges, and opportunities
Although genes have long been appreciated to play a critical role in determining the risk for
pervasive developmental disorders, the specific transcripts contributing to autism spectrum�…
pervasive developmental disorders, the specific transcripts contributing to autism spectrum�…
Genetic architecture in autism spectrum disorder
B Devlin, SW Scherer�- Current opinion in genetics & development, 2012 - Elsevier
Autism spectrum disorder (ASD) is characterized by impairments in reciprocal social
interaction and communication, and by restricted and repetitive behaviors. Family studies�…
interaction and communication, and by restricted and repetitive behaviors. Family studies�…
[HTML][HTML] Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder
Autism spectrum disorder (ASD) refers to a broad spectrum of neurodevelopmental
disorders characterized by three central behavioral symptoms: impaired social interaction�…
disorders characterized by three central behavioral symptoms: impaired social interaction�…