Autism spectrum disorders (ASD) are important neuropsychiatric disorders, currently
estimated to affect approximately 1% of children, with considerable emotional and financial�…

Given the prevalence and societal impact of autism spectrum disorders (ASD), there is an
urgent need to develop innovative preventative strategies and treatments to reduce the�…

Abstract The Autism Spectrum Disorder (ASD) consists of a prevalent and heterogeneous
group of neurodevelopmental diseases representing a severe burden to affected individuals�…

Recent advances in the genetics of autism spectrum disorders (ASDs) are offering new
valuable insights into molecular and cellular mechanisms of pathology. At the same time, the�…

The autism spectrum disorders (ASD) are a heterogeneous set of neurodevelopmental
syndromes defined by impairments in verbal and non-verbal communication, restricted�…

Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An�…

Refined social phenotyping of syndromic and idiopathic forms of autism, combined with
advances in genetics, animal models of syndromes and brain imaging, may facilitate�…

Recent breakthroughs in sequencing technology and technological developments have
made it easier to analyze the entire human genome than ever before. In addition to disease�…

Abstract Autism Spectrum Disorder (ASD) is a highly heterogeneous neurodevelopmental
disorder characterized by deficits in social communication and by patterns of restricted�…

More than a hundred de novo single gene mutations and copy‐number variants have been
implicated in autism, each occurring in a small subset of cases. Mutant mouse models with�…